Matches in Nanopublications for { ?s ?p ?o <http://rdf.disgenet.org/resource/nanopub/NP509985.RAL066A2OU3EdFV2bYjndvO1NV9ij81-qy7qNLjG0i_Ps130_provenance>. }
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- source_evidence_literature type ECO_0000212 NP509985.RAL066A2OU3EdFV2bYjndvO1NV9ij81-qy7qNLjG0i_Ps130_provenance.
- source_evidence_literature label "DisGeNET evidence - LITERATURE" NP509985.RAL066A2OU3EdFV2bYjndvO1NV9ij81-qy7qNLjG0i_Ps130_provenance.
- source_evidence_literature comment "Gene-disease associations inferred from text-mining the literature." NP509985.RAL066A2OU3EdFV2bYjndvO1NV9ij81-qy7qNLjG0i_Ps130_provenance.
- NP509985.RAL066A2OU3EdFV2bYjndvO1NV9ij81-qy7qNLjG0i_Ps130_assertion description "[Here we showed that (a) CXCL12/CXCR4 axis is expressed in PC bone metastasis; (b) exogenous CXCL12 induced MMP-9 expression by PC cells; (c) bone stromal cells and bone tissue conditioned media induced the migration of PC cells in a CXCR4-dependent manner; (d) pharmacological inhibition of PI3 kinase and MAP kinase pathways abrogated CXCL12-induced MMP-9 expression and invasion of PC cells; (e) exogenous CXCL12 induced Akt1 phosphorylation is indispensable for proMMP-9 secretion, migration, and invasion of PC cells; (f) CXCR4 was localized to lipid rafts in PC cells and initiated Akt phosphorylation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP509985.RAL066A2OU3EdFV2bYjndvO1NV9ij81-qy7qNLjG0i_Ps130_provenance.
- NP509985.RAL066A2OU3EdFV2bYjndvO1NV9ij81-qy7qNLjG0i_Ps130_assertion evidence source_evidence_literature NP509985.RAL066A2OU3EdFV2bYjndvO1NV9ij81-qy7qNLjG0i_Ps130_provenance.
- NP509985.RAL066A2OU3EdFV2bYjndvO1NV9ij81-qy7qNLjG0i_Ps130_assertion SIO_000772 16114056 NP509985.RAL066A2OU3EdFV2bYjndvO1NV9ij81-qy7qNLjG0i_Ps130_provenance.
- NP509985.RAL066A2OU3EdFV2bYjndvO1NV9ij81-qy7qNLjG0i_Ps130_assertion wasDerivedFrom befree-2016 NP509985.RAL066A2OU3EdFV2bYjndvO1NV9ij81-qy7qNLjG0i_Ps130_provenance.
- NP509985.RAL066A2OU3EdFV2bYjndvO1NV9ij81-qy7qNLjG0i_Ps130_assertion wasGeneratedBy ECO_0000203 NP509985.RAL066A2OU3EdFV2bYjndvO1NV9ij81-qy7qNLjG0i_Ps130_provenance.
- befree-2016 importedOn "2016-02-19" NP509985.RAL066A2OU3EdFV2bYjndvO1NV9ij81-qy7qNLjG0i_Ps130_provenance.