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- source_evidence_literature type ECO_0000212 NP512538.RAU1rqnO2R2ZJ2-UZjoosvK474GblbQt5I0ROypQuDz_M130_provenance.
- source_evidence_literature label "DisGeNET evidence - LITERATURE" NP512538.RAU1rqnO2R2ZJ2-UZjoosvK474GblbQt5I0ROypQuDz_M130_provenance.
- source_evidence_literature comment "Gene-disease associations inferred from text-mining the literature." NP512538.RAU1rqnO2R2ZJ2-UZjoosvK474GblbQt5I0ROypQuDz_M130_provenance.
- NP512538.RAU1rqnO2R2ZJ2-UZjoosvK474GblbQt5I0ROypQuDz_M130_assertion description "[Glioblastomas frequently carry genetic alterations resulting in an aberrant activation of the phosphoinositol-3-kinase (Pi3k)/protein kinase B (Akt) signalling pathway, including most notably phosphatase and tensin homolog (PTEN) mutation, epidermal growth factor receptor (EGFR) amplification and rearrangement, as well as carboxyl-terminal modulator protein (CTMP) hypermethylation [Knobbe et al., (2004) Hypermethylation and transcriptional downregulation of the carboxyl-terminal modulator protein gene in glioblastomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP512538.RAU1rqnO2R2ZJ2-UZjoosvK474GblbQt5I0ROypQuDz_M130_provenance.
- NP512538.RAU1rqnO2R2ZJ2-UZjoosvK474GblbQt5I0ROypQuDz_M130_assertion evidence source_evidence_literature NP512538.RAU1rqnO2R2ZJ2-UZjoosvK474GblbQt5I0ROypQuDz_M130_provenance.
- NP512538.RAU1rqnO2R2ZJ2-UZjoosvK474GblbQt5I0ROypQuDz_M130_assertion SIO_000772 16150119 NP512538.RAU1rqnO2R2ZJ2-UZjoosvK474GblbQt5I0ROypQuDz_M130_provenance.
- NP512538.RAU1rqnO2R2ZJ2-UZjoosvK474GblbQt5I0ROypQuDz_M130_assertion wasDerivedFrom befree-2016 NP512538.RAU1rqnO2R2ZJ2-UZjoosvK474GblbQt5I0ROypQuDz_M130_provenance.
- NP512538.RAU1rqnO2R2ZJ2-UZjoosvK474GblbQt5I0ROypQuDz_M130_assertion wasGeneratedBy ECO_0000203 NP512538.RAU1rqnO2R2ZJ2-UZjoosvK474GblbQt5I0ROypQuDz_M130_provenance.
- befree-2016 importedOn "2016-02-19" NP512538.RAU1rqnO2R2ZJ2-UZjoosvK474GblbQt5I0ROypQuDz_M130_provenance.