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- source_evidence_literature type ECO_0000212 NP530957.RABoQ0kL6MvwO702dDZhssi68P44hUqyYoBfeSoedRCqc130_provenance.
- source_evidence_literature label "DisGeNET evidence - LITERATURE" NP530957.RABoQ0kL6MvwO702dDZhssi68P44hUqyYoBfeSoedRCqc130_provenance.
- source_evidence_literature comment "Gene-disease associations inferred from text-mining the literature." NP530957.RABoQ0kL6MvwO702dDZhssi68P44hUqyYoBfeSoedRCqc130_provenance.
- NP530957.RABoQ0kL6MvwO702dDZhssi68P44hUqyYoBfeSoedRCqc130_assertion description "[We investigate here the mechanisms by which in vivo abrogation of leptin effects protects SJL/J mice from proteolipid protein peptide PLP(139-151)-induced EAE, an animal model of MS. Blockade of leptin with anti-leptin Abs or with a soluble mouse leptin receptor chimera (ObR:Fc), either before or after onset of EAE, improved clinical score, slowed disease progression, reduced disease relapses, inhibited PLP(139-151)-specific T cell proliferation, and switched cytokine secretion toward a Th2/regulatory profile.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP530957.RABoQ0kL6MvwO702dDZhssi68P44hUqyYoBfeSoedRCqc130_provenance.
- NP530957.RABoQ0kL6MvwO702dDZhssi68P44hUqyYoBfeSoedRCqc130_assertion evidence source_evidence_literature NP530957.RABoQ0kL6MvwO702dDZhssi68P44hUqyYoBfeSoedRCqc130_provenance.
- NP530957.RABoQ0kL6MvwO702dDZhssi68P44hUqyYoBfeSoedRCqc130_assertion SIO_000772 16410832 NP530957.RABoQ0kL6MvwO702dDZhssi68P44hUqyYoBfeSoedRCqc130_provenance.
- NP530957.RABoQ0kL6MvwO702dDZhssi68P44hUqyYoBfeSoedRCqc130_assertion wasDerivedFrom befree-2016 NP530957.RABoQ0kL6MvwO702dDZhssi68P44hUqyYoBfeSoedRCqc130_provenance.
- NP530957.RABoQ0kL6MvwO702dDZhssi68P44hUqyYoBfeSoedRCqc130_assertion wasGeneratedBy ECO_0000203 NP530957.RABoQ0kL6MvwO702dDZhssi68P44hUqyYoBfeSoedRCqc130_provenance.
- befree-2016 importedOn "2016-02-19" NP530957.RABoQ0kL6MvwO702dDZhssi68P44hUqyYoBfeSoedRCqc130_provenance.