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- source_evidence_literature type ECO_0000212 NP602841.RAcw-AHeQXfEuWoYaFBPAT39xnNY9QoMVdvysJl5Bz7E4130_provenance.
- source_evidence_literature label "DisGeNET evidence - LITERATURE" NP602841.RAcw-AHeQXfEuWoYaFBPAT39xnNY9QoMVdvysJl5Bz7E4130_provenance.
- source_evidence_literature comment "Gene-disease associations inferred from text-mining the literature." NP602841.RAcw-AHeQXfEuWoYaFBPAT39xnNY9QoMVdvysJl5Bz7E4130_provenance.
- NP602841.RAcw-AHeQXfEuWoYaFBPAT39xnNY9QoMVdvysJl5Bz7E4130_assertion description "[Analysis of RaLP in melanoma signal transduction pathways revealed that (a) when ectopically expressed in RaLP-negative melanocytes and nonmetastatic melanoma cells, it functions as a substrate of activated insulin-like growth factor-1 and epidermal growth factor receptors and increases Ras/mitogen-activated protein kinase (MAPK) signaling and cell migration, whereas (b) its silencing in RaLP-positive melanoma cells abrogates cell migration in vitro, without affecting MAPK signaling, suggesting that RaLP activates both Ras-dependent and Ras-independent migratory pathways in melanomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP602841.RAcw-AHeQXfEuWoYaFBPAT39xnNY9QoMVdvysJl5Bz7E4130_provenance.
- NP602841.RAcw-AHeQXfEuWoYaFBPAT39xnNY9QoMVdvysJl5Bz7E4130_assertion evidence source_evidence_literature NP602841.RAcw-AHeQXfEuWoYaFBPAT39xnNY9QoMVdvysJl5Bz7E4130_provenance.
- NP602841.RAcw-AHeQXfEuWoYaFBPAT39xnNY9QoMVdvysJl5Bz7E4130_assertion SIO_000772 17409413 NP602841.RAcw-AHeQXfEuWoYaFBPAT39xnNY9QoMVdvysJl5Bz7E4130_provenance.
- NP602841.RAcw-AHeQXfEuWoYaFBPAT39xnNY9QoMVdvysJl5Bz7E4130_assertion wasDerivedFrom befree-2016 NP602841.RAcw-AHeQXfEuWoYaFBPAT39xnNY9QoMVdvysJl5Bz7E4130_provenance.
- NP602841.RAcw-AHeQXfEuWoYaFBPAT39xnNY9QoMVdvysJl5Bz7E4130_assertion wasGeneratedBy ECO_0000203 NP602841.RAcw-AHeQXfEuWoYaFBPAT39xnNY9QoMVdvysJl5Bz7E4130_provenance.
- befree-2016 importedOn "2016-02-19" NP602841.RAcw-AHeQXfEuWoYaFBPAT39xnNY9QoMVdvysJl5Bz7E4130_provenance.