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- source_evidence_literature type ECO_0000212 NP631391.RAnwO-pzywsZ2TxWaW8h96zumAmT1UPY6xsbWAi5MC3B4130_provenance.
- source_evidence_literature label "DisGeNET evidence - LITERATURE" NP631391.RAnwO-pzywsZ2TxWaW8h96zumAmT1UPY6xsbWAi5MC3B4130_provenance.
- source_evidence_literature comment "Gene-disease associations inferred from text-mining the literature." NP631391.RAnwO-pzywsZ2TxWaW8h96zumAmT1UPY6xsbWAi5MC3B4130_provenance.
- NP631391.RAnwO-pzywsZ2TxWaW8h96zumAmT1UPY6xsbWAi5MC3B4130_assertion description "[We investigate here the mechanisms by which in vivo abrogation of leptin effects protects SJL/J mice from proteolipid protein peptide PLP(139-151)-induced EAE, an animal model of MS. Blockade of leptin with anti-leptin Abs or with a soluble mouse leptin receptor chimera (ObR:Fc), either before or after onset of EAE, improved clinical score, slowed disease progression, reduced disease relapses, inhibited PLP(139-151)-specific T cell proliferation, and switched cytokine secretion toward a Th2/regulatory profile.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP631391.RAnwO-pzywsZ2TxWaW8h96zumAmT1UPY6xsbWAi5MC3B4130_provenance.
- NP631391.RAnwO-pzywsZ2TxWaW8h96zumAmT1UPY6xsbWAi5MC3B4130_assertion evidence source_evidence_literature NP631391.RAnwO-pzywsZ2TxWaW8h96zumAmT1UPY6xsbWAi5MC3B4130_provenance.
- NP631391.RAnwO-pzywsZ2TxWaW8h96zumAmT1UPY6xsbWAi5MC3B4130_assertion SIO_000772 16410832 NP631391.RAnwO-pzywsZ2TxWaW8h96zumAmT1UPY6xsbWAi5MC3B4130_provenance.
- NP631391.RAnwO-pzywsZ2TxWaW8h96zumAmT1UPY6xsbWAi5MC3B4130_assertion wasDerivedFrom befree-20150227 NP631391.RAnwO-pzywsZ2TxWaW8h96zumAmT1UPY6xsbWAi5MC3B4130_provenance.
- NP631391.RAnwO-pzywsZ2TxWaW8h96zumAmT1UPY6xsbWAi5MC3B4130_assertion wasGeneratedBy ECO_0000203 NP631391.RAnwO-pzywsZ2TxWaW8h96zumAmT1UPY6xsbWAi5MC3B4130_provenance.
- befree-20150227 importedOn "2015-02-27" NP631391.RAnwO-pzywsZ2TxWaW8h96zumAmT1UPY6xsbWAi5MC3B4130_provenance.