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- source_evidence_literature type ECO_0000212 NP810634.RAP-1Aq3A3yYQhGRDVjbTizkbo-OEQka_A7dkD8lvDKKY130_provenance.
- source_evidence_literature label "DisGeNET evidence - LITERATURE" NP810634.RAP-1Aq3A3yYQhGRDVjbTizkbo-OEQka_A7dkD8lvDKKY130_provenance.
- source_evidence_literature comment "Gene-disease associations inferred from text-mining the literature." NP810634.RAP-1Aq3A3yYQhGRDVjbTizkbo-OEQka_A7dkD8lvDKKY130_provenance.
- NP810634.RAP-1Aq3A3yYQhGRDVjbTizkbo-OEQka_A7dkD8lvDKKY130_assertion description "[At least three mechanisms are thought to contribute to the metastasis-suppressive effect of Nm23-H1: (a) its histidine kinase activity toward ATP-citrate lyase, aldolase C, and the kinase suppressor of ras, with the last inactivating mitogen-activated protein kinase signaling; (b) binding proteins that titer out 'free' Nm23-H1 and inhibit its ability to suppress metastasis; and (c) altered gene expression downstream of Nm23-H1, particularly an inverse association with the lysophosphatidic acid receptor endothelial differentiation gene-28 (EDG2).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP810634.RAP-1Aq3A3yYQhGRDVjbTizkbo-OEQka_A7dkD8lvDKKY130_provenance.
- NP810634.RAP-1Aq3A3yYQhGRDVjbTizkbo-OEQka_A7dkD8lvDKKY130_assertion evidence source_evidence_literature NP810634.RAP-1Aq3A3yYQhGRDVjbTizkbo-OEQka_A7dkD8lvDKKY130_provenance.
- NP810634.RAP-1Aq3A3yYQhGRDVjbTizkbo-OEQka_A7dkD8lvDKKY130_assertion SIO_000772 18698018 NP810634.RAP-1Aq3A3yYQhGRDVjbTizkbo-OEQka_A7dkD8lvDKKY130_provenance.
- NP810634.RAP-1Aq3A3yYQhGRDVjbTizkbo-OEQka_A7dkD8lvDKKY130_assertion wasDerivedFrom befree-20150227 NP810634.RAP-1Aq3A3yYQhGRDVjbTizkbo-OEQka_A7dkD8lvDKKY130_provenance.
- NP810634.RAP-1Aq3A3yYQhGRDVjbTizkbo-OEQka_A7dkD8lvDKKY130_assertion wasGeneratedBy ECO_0000203 NP810634.RAP-1Aq3A3yYQhGRDVjbTizkbo-OEQka_A7dkD8lvDKKY130_provenance.
- befree-20150227 importedOn "2015-02-27" NP810634.RAP-1Aq3A3yYQhGRDVjbTizkbo-OEQka_A7dkD8lvDKKY130_provenance.