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- source_evidence_literature type ECO_0000212 NP852457.RAlcHiOW3KZFnLe9GezXGM5o5YjCykqindiFfmvL15Y7Y130_provenance.
- source_evidence_literature label "DisGeNET evidence - LITERATURE" NP852457.RAlcHiOW3KZFnLe9GezXGM5o5YjCykqindiFfmvL15Y7Y130_provenance.
- source_evidence_literature comment "Gene-disease associations inferred from text-mining the literature." NP852457.RAlcHiOW3KZFnLe9GezXGM5o5YjCykqindiFfmvL15Y7Y130_provenance.
- NP852457.RAlcHiOW3KZFnLe9GezXGM5o5YjCykqindiFfmvL15Y7Y130_assertion description "[To better understand the molecular mechanisms of the antiproliferative action of this BK antagonist in EOC cells, we performed gene expression profiling in TOV-21 and TOV-112 cells following treatment with 10 ?M BKM-570 for 24 h. BKM-570 displayed similar cytotoxic effects in the two cell lines analyzed, as genes with previously shown involvement in apoptosis/antiapoptosis and cell adhesion were proportionally upregulated and downregulated in both cell lines, whereas genes involved in basic cellular mechanisms, including cell growth and maintenance, metabolism, cell cycle control, inflammatory and immune response, signal transduction, protein biosynthesis, transcription regulation, and transport, were predominantly downregulated upon treatment.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP852457.RAlcHiOW3KZFnLe9GezXGM5o5YjCykqindiFfmvL15Y7Y130_provenance.
- NP852457.RAlcHiOW3KZFnLe9GezXGM5o5YjCykqindiFfmvL15Y7Y130_assertion evidence source_evidence_literature NP852457.RAlcHiOW3KZFnLe9GezXGM5o5YjCykqindiFfmvL15Y7Y130_provenance.
- NP852457.RAlcHiOW3KZFnLe9GezXGM5o5YjCykqindiFfmvL15Y7Y130_assertion SIO_000772 21078129 NP852457.RAlcHiOW3KZFnLe9GezXGM5o5YjCykqindiFfmvL15Y7Y130_provenance.
- NP852457.RAlcHiOW3KZFnLe9GezXGM5o5YjCykqindiFfmvL15Y7Y130_assertion wasDerivedFrom befree-2016 NP852457.RAlcHiOW3KZFnLe9GezXGM5o5YjCykqindiFfmvL15Y7Y130_provenance.
- NP852457.RAlcHiOW3KZFnLe9GezXGM5o5YjCykqindiFfmvL15Y7Y130_assertion wasGeneratedBy ECO_0000203 NP852457.RAlcHiOW3KZFnLe9GezXGM5o5YjCykqindiFfmvL15Y7Y130_provenance.
- befree-2016 importedOn "2016-02-19" NP852457.RAlcHiOW3KZFnLe9GezXGM5o5YjCykqindiFfmvL15Y7Y130_provenance.