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- source_evidence_literature type ECO_0000212 NP914397.RAEUvlChoxjIfHNi11GZXgh2ol4wOxvcmpR-K5ucRDbQ0130_provenance.
- source_evidence_literature label "DisGeNET evidence - LITERATURE" NP914397.RAEUvlChoxjIfHNi11GZXgh2ol4wOxvcmpR-K5ucRDbQ0130_provenance.
- source_evidence_literature comment "Gene-disease associations inferred from text-mining the literature." NP914397.RAEUvlChoxjIfHNi11GZXgh2ol4wOxvcmpR-K5ucRDbQ0130_provenance.
- NP914397.RAEUvlChoxjIfHNi11GZXgh2ol4wOxvcmpR-K5ucRDbQ0130_assertion description "[We found that long-term exposure to hypoxia a) significantly inhibited lung cancer tumor growth in xenograft and orthotopic models in rats, b) significantly reduced lymphatic metastasis of the lung cancer in rats and decreased lung metastasis of Lewis lung carcinoma in mice, c) reduced lung cancer cell proliferation and cell cycle progression in vitro, d) decreased growth of the tumors from hypoxia-pretreated A549 cells, e) decreased Na+-K+ ATPase ?1 expression in hypoxic lung cancer tumors, and f) increased expression of hypoxia inducible factors (HIF1? and HIF2?) but decreased microvessel density in the lung cancer tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP914397.RAEUvlChoxjIfHNi11GZXgh2ol4wOxvcmpR-K5ucRDbQ0130_provenance.
- NP914397.RAEUvlChoxjIfHNi11GZXgh2ol4wOxvcmpR-K5ucRDbQ0130_assertion evidence source_evidence_literature NP914397.RAEUvlChoxjIfHNi11GZXgh2ol4wOxvcmpR-K5ucRDbQ0130_provenance.
- NP914397.RAEUvlChoxjIfHNi11GZXgh2ol4wOxvcmpR-K5ucRDbQ0130_assertion SIO_000772 21812995 NP914397.RAEUvlChoxjIfHNi11GZXgh2ol4wOxvcmpR-K5ucRDbQ0130_provenance.
- NP914397.RAEUvlChoxjIfHNi11GZXgh2ol4wOxvcmpR-K5ucRDbQ0130_assertion wasDerivedFrom befree-2016 NP914397.RAEUvlChoxjIfHNi11GZXgh2ol4wOxvcmpR-K5ucRDbQ0130_provenance.
- NP914397.RAEUvlChoxjIfHNi11GZXgh2ol4wOxvcmpR-K5ucRDbQ0130_assertion wasGeneratedBy ECO_0000203 NP914397.RAEUvlChoxjIfHNi11GZXgh2ol4wOxvcmpR-K5ucRDbQ0130_provenance.
- befree-2016 importedOn "2016-02-19" NP914397.RAEUvlChoxjIfHNi11GZXgh2ol4wOxvcmpR-K5ucRDbQ0130_provenance.