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- source_evidence_literature type ECO_0000212 NP942298.RAi8Pd-IZSby4emZS39LaEc-QkflS0UOu7N6CyMqiRwDw130_provenance.
- source_evidence_literature label "DisGeNET evidence - LITERATURE" NP942298.RAi8Pd-IZSby4emZS39LaEc-QkflS0UOu7N6CyMqiRwDw130_provenance.
- source_evidence_literature comment "Gene-disease associations inferred from text-mining the literature." NP942298.RAi8Pd-IZSby4emZS39LaEc-QkflS0UOu7N6CyMqiRwDw130_provenance.
- NP942298.RAi8Pd-IZSby4emZS39LaEc-QkflS0UOu7N6CyMqiRwDw130_assertion description "[This interaction is functional; overexpression of FTO delays the dephosphorylation of cAMP response element-binding protein (CREB) in human neuroblastoma (SK-N-SH) cells, which in turn leads to a dramatic increase in the expression of the CREB targets neuropeptide receptor 1 (NPY1R) and brain-derived neurotrophic factor (BDNF), which already are known to regulate food intake and energy homeostasis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP942298.RAi8Pd-IZSby4emZS39LaEc-QkflS0UOu7N6CyMqiRwDw130_provenance.
- NP942298.RAi8Pd-IZSby4emZS39LaEc-QkflS0UOu7N6CyMqiRwDw130_assertion evidence source_evidence_literature NP942298.RAi8Pd-IZSby4emZS39LaEc-QkflS0UOu7N6CyMqiRwDw130_provenance.
- NP942298.RAi8Pd-IZSby4emZS39LaEc-QkflS0UOu7N6CyMqiRwDw130_assertion SIO_000772 24488767 NP942298.RAi8Pd-IZSby4emZS39LaEc-QkflS0UOu7N6CyMqiRwDw130_provenance.
- NP942298.RAi8Pd-IZSby4emZS39LaEc-QkflS0UOu7N6CyMqiRwDw130_assertion wasDerivedFrom befree-20150227 NP942298.RAi8Pd-IZSby4emZS39LaEc-QkflS0UOu7N6CyMqiRwDw130_provenance.
- NP942298.RAi8Pd-IZSby4emZS39LaEc-QkflS0UOu7N6CyMqiRwDw130_assertion wasGeneratedBy ECO_0000203 NP942298.RAi8Pd-IZSby4emZS39LaEc-QkflS0UOu7N6CyMqiRwDw130_provenance.
- befree-20150227 importedOn "2015-02-27" NP942298.RAi8Pd-IZSby4emZS39LaEc-QkflS0UOu7N6CyMqiRwDw130_provenance.