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- source_evidence_literature type ECO_0000212 NP996476.RA2EIqeYFQhe_TuUWxZbOYP21J3i9IPD1_FLRpFQp2E9o130_provenance.
- source_evidence_literature label "DisGeNET evidence - LITERATURE" NP996476.RA2EIqeYFQhe_TuUWxZbOYP21J3i9IPD1_FLRpFQp2E9o130_provenance.
- source_evidence_literature comment "Gene-disease associations inferred from text-mining the literature." NP996476.RA2EIqeYFQhe_TuUWxZbOYP21J3i9IPD1_FLRpFQp2E9o130_provenance.
- NP996476.RA2EIqeYFQhe_TuUWxZbOYP21J3i9IPD1_FLRpFQp2E9o130_assertion description "[Using murine BaF3 cells, stably transformed with six different FGFR1 fusion genes, as well as human KG1 cells expressing activated chimeric FGFR1 and five newly established murine SCLL cell lines, we show that ponatinib (<50 nM) can effectively inhibit phosphoactivation of the fusion kinases and their downstream effectors, such as PLC?, Stat5 and Src.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP996476.RA2EIqeYFQhe_TuUWxZbOYP21J3i9IPD1_FLRpFQp2E9o130_provenance.
- NP996476.RA2EIqeYFQhe_TuUWxZbOYP21J3i9IPD1_FLRpFQp2E9o130_assertion evidence source_evidence_literature NP996476.RA2EIqeYFQhe_TuUWxZbOYP21J3i9IPD1_FLRpFQp2E9o130_provenance.
- NP996476.RA2EIqeYFQhe_TuUWxZbOYP21J3i9IPD1_FLRpFQp2E9o130_assertion SIO_000772 22781593 NP996476.RA2EIqeYFQhe_TuUWxZbOYP21J3i9IPD1_FLRpFQp2E9o130_provenance.
- NP996476.RA2EIqeYFQhe_TuUWxZbOYP21J3i9IPD1_FLRpFQp2E9o130_assertion wasDerivedFrom befree-2016 NP996476.RA2EIqeYFQhe_TuUWxZbOYP21J3i9IPD1_FLRpFQp2E9o130_provenance.
- NP996476.RA2EIqeYFQhe_TuUWxZbOYP21J3i9IPD1_FLRpFQp2E9o130_assertion wasGeneratedBy ECO_0000203 NP996476.RA2EIqeYFQhe_TuUWxZbOYP21J3i9IPD1_FLRpFQp2E9o130_provenance.
- befree-2016 importedOn "2016-02-19" NP996476.RA2EIqeYFQhe_TuUWxZbOYP21J3i9IPD1_FLRpFQp2E9o130_provenance.