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- _6 label "Selventa" provenance.
- large_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All rights reserved." provenance.
- _5 value "Forskolin did not promote the binding of 14-3-3 proteins to PDE3A (Figures 2A and 5A). However, using the pSer312-PDE3A antibodies, we found that forskolin stimulated the phosphorylation of PDE3A at Ser312 (Figures 5A and 5C). This residue lies within a sequence SHRRTS312LPCIP that conforms to a consensus site for PKA. The forskolin-stimulated phosphorylation of Ser312 was inhibited by the PKA inhibitor H-89 (Figure 5C), and by mimosine and aphidicolin (Figure 5A), but not by inhibitors of PI3K (LY 294002), mTOR (mammalian target of rapamycin) (rapamycin) or the MAPK cascade (U0126) (Figure 5C; see [35] for inhibitor specificities), nor by H-7 (results not shown)." provenance.
- _5 wasQuotedFrom 16153182 provenance.
- assertion hadPrimarySource 16153182 provenance.
- large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
- large_corpus.bel description "Approximately 61,000 statements." provenance.
- assertion wasDerivedFrom large_corpus.bel provenance.
- assertion wasDerivedFrom _5 provenance.
- large_corpus.bel authoredBy _6 provenance.
- large_corpus.bel version "1.4" provenance.