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Matches in Nanopublications for { ?s ?p ?o <http://www.tkuhn.ch/bel2nanopub/RAH52g0s4ygXxx2k1hgGl4FkPQagZSCFodF8AZfHv3LMk#provenance>. }

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_7 label "Selventa" provenance.
_6 value "Figure 4 Anti-apoptotic brakes at the mitochondrion. Black lines represent apoptotic pathways, red lines indicate inhibition. BCL2 (B-cell leukaemia lymphoma-2) and ?B-crystallin prevent mitochondrial release of the apoptogenic factors AIF (apoptosisinducing factor), cytochrome c (cyto c), HTRA2/OMI (high temperature requirement serine protease 2) and SMAC/DIABLO (second-mitochondrial-derived activator of caspases) into the cytosol by the binding and sequestration of BAX (B-cell lymphoma 2-associated protein X) and pro-apoptic BCL2 BAX-like molecules, BAK (BCL2 agonist killer 1) and BOK (BCL2-related ovarian killer protein) in the cytosol. APC (activated protein C) might prevent AIF release by increasing BCL2 expression. BAX translocation to the outer mitochondrial membrane is prevented by HSP70 (heat shock protein 70) and its co-chaperone HSP40(DNAJL1/DNAJL2). Meanwhile, membrane depolarization is prevented by the uncoupling properties of UCP2 (uncoupling protein 2) and the free radical scavenging properties of GIF (growth inhibitory factor). BH3, BCL2 homology domain 3; cIAP1, cellular apoptosis inhibitor 1; ENDOG, endonuclease G; HSP27, heat shock protein 27; IAP, inhibitor of apoptosis protein; XIAP, X-chromosome linked inhibitor of apoptosis protein." provenance.
_6 wasQuotedFrom 15322527 provenance.
assertion hadPrimarySource 15322527 provenance.
large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
large_corpus.bel description "Approximately 61,000 statements." provenance.
assertion wasDerivedFrom _6 provenance.
assertion wasDerivedFrom large_corpus.bel provenance.
large_corpus.bel authoredBy _7 provenance.
large_corpus.bel version "1.4" provenance.