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- _6 label "Selventa" provenance.
- large_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All rights reserved." provenance.
- _5 value "Treatment of human umbilical vein endothelial cells (HUVECs) with betacellulin (BTC, 10 ng/ml) increased phosphorylation of two MAPKs, ERK1 (p44MAPK) and ERK2 (p42MAPK) and AKT as early as 1 minute and produced a maximal effect at 5 minutes, which declined and returned to control levels at 60 minutes. BTC treatment also phosphorylated all three Erb receptors ErbB2, ErbB3, and ErbB4 but not ErbB1. BTC induced phosphorylation of MAPK and AKT was not suppressed by a selectilvely inhibitory concentration of ErbB1 receptor inhibitor, AG1478), suggesting that BTC induced MAPK and AKT activation was mediated through ErbB4 homodimer, ErbB2/ErbB3, or ErbB2/ErbB4." provenance.
- _5 wasQuotedFrom 12475887 provenance.
- assertion hadPrimarySource 12475887 provenance.
- large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
- large_corpus.bel description "Approximately 61,000 statements." provenance.
- assertion wasDerivedFrom large_corpus.bel provenance.
- assertion wasDerivedFrom _5 provenance.
- large_corpus.bel authoredBy _6 provenance.
- large_corpus.bel version "20131211" provenance.