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- _6 label "Selventa" provenance.
- large_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All rights reserved." provenance.
- _5 value "There are several signal transduction mechanisms that modulate intracellular calcium concentration and therefore the state of vascular tone. Three different mechanisms will be described here: 1) phosphatidylinositol pathway, 2) Gs-protein-coupled pathway, and 3) nitric oxide-cGMP pathway The phosphatidylinositol pathway (shown to the right) in VSM is similar to that found in the heart. Norepinephrine (NE) acting via a1-adrenoceptors, angiotensin II (AII) acting via AII receptors, and endothelin-I (ET-1) acting through ETA receptors activate phospholipase C (PL-C) causing the formation of inositol triphosphate (IP3) from phosphatidylinositol (PIP2)." provenance.
- _5 wasQuotedFrom _4 provenance.
- assertion hadPrimarySource _4 provenance.
- large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
- _4 title "Cardiovascular Physiology Concepts" provenance.
- large_corpus.bel description "Approximately 61,000 statements." provenance.
- assertion wasDerivedFrom large_corpus.bel provenance.
- assertion wasDerivedFrom _5 provenance.
- large_corpus.bel authoredBy _6 provenance.
- large_corpus.bel version "20131211" provenance.
- _4 identifier "Cardiovascular Physiology Concepts" provenance.
- _4 type "Other" provenance.