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- _5 label "Selventa" provenance.
- _5 comment "support@belframework.org" provenance.
- small_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All Rights Reserved." provenance.
- small_corpus.bel license "Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License" provenance.
- _4 value "To determine whether PKA-induced PKB activation accounts for GSK-3 phosphorylation after treatment with 8-Br-cAMP, forskolin, or isoproterenol, PKB phosphorylation at serine 473 and threonine 308, which is crucial for activation of PKB (20), was assessed. As expected, insulin and IGF-1 strongly stimulated phosphorylation of PKB at serine 473 in NIH 3T3 or Rat1 cells (Fig. 2B). In contrast, 8-Br-cAMP, forskolin, and isoproterenol did not significantly alter PKB phosphorylation at serine 473 (Fig. 2B). Similar results were obtained with a threonine 308 phosphorylation-specific antibody (data not shown)." provenance.
- _4 wasQuotedFrom 11035810 provenance.
- assertion hadPrimarySource 11035810 provenance.
- small_corpus.bel title "BEL Framework Small Corpus Document" provenance.
- small_corpus.bel description "Approximately 2000 hand curated statements drawn from 57 PubMeds." provenance.
- assertion wasDerivedFrom small_corpus.bel provenance.
- assertion wasDerivedFrom _4 provenance.
- small_corpus.bel authoredBy _5 provenance.
- small_corpus.bel version "1.6" provenance.