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- _6 label "Selventa" provenance.
- large_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All rights reserved." provenance.
- _5 value "Two types of receptors have been identified for FGF-2: high affinity tyrosine-kinase FGF receptors (FGFRs) (123) and low affinity heparan sulfate proteoglycans (HSPGs). Thus far, at least four members of FGFRs have been identified. They represent low number (approx. 10,000 per cell), but high affinity sites (Kd of 20-600 pM). Low affinity binding sites (Kd of 2-20 nM) with high capacity (approx. 1 million sites per cell) were identified as proteoglycans, including syndecan and perlecan, containing heparan sulfate side chains (202). These HSPGs are found in the ECM, the basement membrane and the cell surface. It has been suggested that binding of FGF-2 to HSPGs result in protection of FGF-2 from inactivation in the extracellular environment and in storage of FGF-2 in the ECM and basement membrane." provenance.
- _5 wasQuotedFrom 11172729 provenance.
- assertion hadPrimarySource 11172729 provenance.
- large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
- large_corpus.bel description "Approximately 61,000 statements." provenance.
- assertion wasDerivedFrom large_corpus.bel provenance.
- assertion wasDerivedFrom _5 provenance.
- large_corpus.bel authoredBy _6 provenance.
- large_corpus.bel version "20131211" provenance.