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- _5 label "Selventa" provenance.
- large_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All rights reserved." provenance.
- _4 value "ET-1, as well as PGE2, induced HEY and OVCA433 cells revealed a significant increase in the level of phosphorylated EGFR. Pretreatment of HEY cells with the specific EGFR kinase inhibitor, AG1478, as well as with the Src tyrosine kinase inhibitor, PP2 significantly reduced both ET-1 and PGE2 induced EGFR phosphorylation, indicating that activation of Src is essential for ET-1- and PGE2 induced EGFR transactivation. The interruption of EGFR signaling induced by AG1478, as well as by PP2, resulted in a concomitant reduction of PGE2 secretion, as well as of VEGF expression at protein and mRNA levels, indicating that Src mediated EGFR transactivation is involved in ET-1 induced PGE2 and VEGF production." provenance.
- _4 wasQuotedFrom 12907686 provenance.
- assertion hadPrimarySource 12907686 provenance.
- large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
- large_corpus.bel description "Approximately 61,000 statements." provenance.
- assertion wasDerivedFrom large_corpus.bel provenance.
- assertion wasDerivedFrom _4 provenance.
- large_corpus.bel authoredBy _5 provenance.
- large_corpus.bel version "1.4" provenance.