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- _6 label "Selventa" provenance.
- _6 comment "support@belframework.org" provenance.
- small_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All Rights Reserved." provenance.
- small_corpus.bel license "Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License" provenance.
- _5 value "Adhesion of HT-29 cells on a monolayer of HUVEC pretreated with TNF? was dependent on E-selectin expression but was independent of SAPK2/p38 activity of both HUVEC and tumor cells. The adhesion of HT-29 cells to E-selectin-expressing HUVEC led to the activation of SAPK2/p38 in the tumor cells as reflected by the increased phosphorylation of the actin-polymerizing factor HSP27 by mitogen-activated protein kinase 2/3, a direct target of SAPK2/p38. Moreover, a recombinant E-selectin/Fc chimera quickly increased the activation of SAPK2/p38 in HT-29 cells. Blocking the increased activity of SAPK2/p38 of HT-29 cells by SB203580 or by expressing a dominant negative form of SAPK2/p38 inhibited their transendothelial migration." provenance.
- _5 wasQuotedFrom 11448946 provenance.
- assertion hadPrimarySource 11448946 provenance.
- small_corpus.bel title "BEL Framework Small Corpus Document" provenance.
- small_corpus.bel description "Approximately 2000 hand curated statements drawn from 57 PubMeds." provenance.
- assertion wasDerivedFrom small_corpus.bel provenance.
- assertion wasDerivedFrom _5 provenance.
- small_corpus.bel authoredBy _6 provenance.
- small_corpus.bel version "1.6" provenance.