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- _6 label "Selventa" provenance.
- large_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All rights reserved." provenance.
- _5 value "Figure 2. A schematic diagram shows the cellular signalling pathway by which ENaC is regulated by the hormones aldosterone and insulin. The effect of aldosterone and insulin is mediated via a phosphatidylinositol 3-kinase (PI3K) and phosphoinositide-dependent protein kinase (PDK) pathway, which activates serum and glucocorticoid-dependent protein kinase (Sgk1) and protein kinase B (Akt1). Both Sgk1 and Akt1 phosphorylate Nedd4-2. The phosphorylated form of Nedd4-2 interacts with 14-3-3, preventing it from binding to and inducing ubiquitination of ENaC. " provenance.
- _5 wasQuotedFrom 18197893 provenance.
- assertion hadPrimarySource 18197893 provenance.
- large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
- large_corpus.bel description "Approximately 61,000 statements." provenance.
- assertion wasDerivedFrom _5 provenance.
- assertion wasDerivedFrom large_corpus.bel provenance.
- large_corpus.bel authoredBy _6 provenance.
- large_corpus.bel version "20131211" provenance.