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- _6 label "Selventa" provenance.
- large_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All rights reserved." provenance.
- _5 value "It has been proposed that this regulation of PDE4D and other PDE4 long forms by MAPK constitutes feedback regulation. Inhibition of the PDE4 activity induces an increase in cAMP, and it has been speculated that the local activation of PKA in turn suppresses the MAPK cascade via phosphorylation of RAF (50). Pharmacological manipulation of the aortic smooth muscle cells shows that PKA phosphorylation and activation of PDE4D5 overcomes or obliterates the initial inhibition due to MAPK phosphorylation" provenance.
- _5 wasQuotedFrom 12493749 provenance.
- assertion hadPrimarySource 12493749 provenance.
- large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
- large_corpus.bel description "Approximately 61,000 statements." provenance.
- assertion wasDerivedFrom _5 provenance.
- assertion wasDerivedFrom large_corpus.bel provenance.
- large_corpus.bel authoredBy _6 provenance.
- large_corpus.bel version "20131211" provenance.