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- _6 label "Selventa" provenance.
- large_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All rights reserved." provenance.
- _5 value "The signaling cascades from these two receptors join at IKK-like kinase, IKK-i and TBK-1, and these kinases play an important role in phosphorylation and activation of the type-I IFN transcription factor, interferon regulatory factor-3 (IRF-3) ... Qin et al. suggested that IRF-3 is autoinhibited in the resting state by interaction between the N-terminal helix of RD and SRR but that the phosphorylation of Ser385 and/or Ser386 in the 2S site induces destabilization of SRR leading to exposure and phosphorylation of Ser396, Ser398 and other Ser/Thr residues (Ser402, Thr404, Ser405) in the 5ST site that can disrupt the autoinhibitory structure (Qin et al. 2003). " provenance.
- _5 wasQuotedFrom 20604809 provenance.
- assertion hadPrimarySource 20604809 provenance.
- large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
- large_corpus.bel description "Approximately 61,000 statements." provenance.
- assertion wasDerivedFrom _5 provenance.
- assertion wasDerivedFrom large_corpus.bel provenance.
- large_corpus.bel authoredBy _6 provenance.
- large_corpus.bel version "20131211" provenance.