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- _7 label "Selventa" provenance.
- _7 comment "support@belframework.org" provenance.
- small_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All Rights Reserved." provenance.
- small_corpus.bel license "Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License" provenance.
- _6 value "To determine whether LRIG1 expression influences the ubiquitination and degradation rate of ErbB receptors in the inducible expression system, we focused on the effect of LRIG1 expression on the properties of EGFR in the PC3-LRIG1 cells. Similar to the results with transfected 293T cells (Fig. 3), we observed that the induction of LRIG1 expression markedly augmented the ubiquitination of EGFR in response to EGF treatment (Fig. 5A). This potentiation of ligand-stimulated EGFR ubiquitination correlated with a suppression of EGFR tyrosine phosphorylation and receptor levels after growth factor treatment." provenance.
- _6 wasQuotedFrom 15345710 provenance.
- assertion hadPrimarySource 15345710 provenance.
- small_corpus.bel title "BEL Framework Small Corpus Document" provenance.
- small_corpus.bel description "Approximately 2000 hand curated statements drawn from 57 PubMeds." provenance.
- assertion wasDerivedFrom small_corpus.bel provenance.
- assertion wasDerivedFrom _6 provenance.
- small_corpus.bel authoredBy _7 provenance.
- small_corpus.bel version "1.6" provenance.