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- _7 label "Selventa" provenance.
- _7 comment "support@belframework.org" provenance.
- small_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All Rights Reserved." provenance.
- small_corpus.bel license "Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License" provenance.
- _6 value "Here we tested how expression of COUP?TFI affected TCDD activity from the natural ERE sequences from the pS2 and c-fos promoters in transiently transfected MCF-7 cells. E2 alone stimulated a 1.6- to 2.1-fold induction in luciferase activity from the pS2 ERE (Fig. 8A). 4-OHT blocked the E2 activity, indicating the specificity of the induction by ER. TCDD alone gave a 1.4-fold induction in luciferase activity. Cotreatment with TCDD suppressed E2-stimulated luciferase activity. COUP?TFI inhibited both E2- and TCDD-stimulated luciferase activity from pS2." provenance.
- _6 wasQuotedFrom 10620335 provenance.
- assertion hadPrimarySource 10620335 provenance.
- small_corpus.bel title "BEL Framework Small Corpus Document" provenance.
- small_corpus.bel description "Approximately 2000 hand curated statements drawn from 57 PubMeds." provenance.
- assertion wasDerivedFrom _6 provenance.
- assertion wasDerivedFrom small_corpus.bel provenance.
- small_corpus.bel authoredBy _7 provenance.
- small_corpus.bel version "20131211" provenance.