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- _7 label "Selventa" provenance.
- large_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All rights reserved." provenance.
- _6 value "As shown in Figure 2A, quiescent A549 cells and HAECs did not have any detectable Rb?Raf-1 interaction, but stimulation with nicotine induced a robust Rb?Raf-1 interaction. The Rb?Raf-1 interaction was detected up to 2 hours after nicotine stimulation and dissipated within 4 hours. The binding between Rb and Raf-1 was also observed in lung cancer cell lines H23, H441, and H226 (Figure 2B) as well as in primary lung cells such as SAECs, NHBEs, and HMEC-Ls stimulated with 1 ?M nicotine (Figure 2C). Nicotine-induced Rb?Raf-1 interaction was abolished by ?-bungarotoxin and MAA, suggesting a role for ?7-nAChR in this binding (Figure 2D)." provenance.
- _6 wasQuotedFrom 16862215 provenance.
- assertion hadPrimarySource 16862215 provenance.
- large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
- large_corpus.bel description "Approximately 61,000 statements." provenance.
- assertion wasDerivedFrom large_corpus.bel provenance.
- assertion wasDerivedFrom _6 provenance.
- large_corpus.bel authoredBy _7 provenance.
- large_corpus.bel version "20131211" provenance.