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- _6 label "Selventa" provenance.
- large_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All rights reserved." provenance.
- _5 value "The insulin receptor and some of its substrates are also subject to serine/threonine phosphorylation. Data from some experimental models suggest that this might represent a mechanism by which signaling is terminated, or perhaps attenuated in states of insulin resistance. Numerous in vitro studies have shown that the tyrosine kinase activity of the receptor decreases as a consequence of serine/threonine phosphorylation. This might occur via feedback \"retrophosphorylation\" events in which the receptor or IRS proteins are serine phosphorylated by GSK3 or mTOR, both of which are activated downstream of IRS phosphorylation." provenance.
- _5 wasQuotedFrom 11849969 provenance.
- assertion hadPrimarySource 11849969 provenance.
- large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
- large_corpus.bel description "Approximately 61,000 statements." provenance.
- assertion wasDerivedFrom large_corpus.bel provenance.
- assertion wasDerivedFrom _5 provenance.
- large_corpus.bel authoredBy _6 provenance.
- large_corpus.bel version "1.4" provenance.