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- _8 label "Selventa" provenance.
- large_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All rights reserved." provenance.
- _7 value "the SGK promoter contains consensus DNA elements for Smad and Fast-1 binding (hatched boxes labeled SMAD 3/4 and Fast-1 in figure 2) that are activated by TGF-beta receptor signaling, This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors. This protein can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin. Alternatively spliced transcript variants encoding the same protein have been observed." provenance.
- _7 wasQuotedFrom 12649597 provenance.
- assertion hadPrimarySource 12649597 provenance.
- large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
- large_corpus.bel description "Approximately 61,000 statements." provenance.
- assertion wasDerivedFrom large_corpus.bel provenance.
- assertion wasDerivedFrom _7 provenance.
- large_corpus.bel authoredBy _8 provenance.
- large_corpus.bel version "20131211" provenance.