Matches in Nanopublications for { ?s ?p "In fact, Skp2 overexpression was shown to induce the transcription of c-Myc target genes suggesting that Skp2 acts as a transcription coactivator of c-Myc. Skp2 can concurrently lead to degradation of tumor suppressors (p27, p57, p21 and p130) and to activation of an oncogene (c-Myc). While Skp2-deficient mice, which should have decreased c-Myc activity, can develop almost normally" ?g. }
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- _3 value "In fact, Skp2 overexpression was shown to induce the transcription of c-Myc target genes suggesting that Skp2 acts as a transcription coactivator of c-Myc. Skp2 can concurrently lead to degradation of tumor suppressors (p27, p57, p21 and p130) and to activation of an oncogene (c-Myc). While Skp2-deficient mice, which should have decreased c-Myc activity, can develop almost normally" provenance.
- _3 value "In fact, Skp2 overexpression was shown to induce the transcription of c-Myc target genes suggesting that Skp2 acts as a transcription coactivator of c-Myc. Skp2 can concurrently lead to degradation of tumor suppressors (p27, p57, p21 and p130) and to activation of an oncogene (c-Myc). While Skp2-deficient mice, which should have decreased c-Myc activity, can develop almost normally" provenance.
- _3 value "In fact, Skp2 overexpression was shown to induce the transcription of c-Myc target genes suggesting that Skp2 acts as a transcription coactivator of c-Myc. Skp2 can concurrently lead to degradation of tumor suppressors (p27, p57, p21 and p130) and to activation of an oncogene (c-Myc). While Skp2-deficient mice, which should have decreased c-Myc activity, can develop almost normally" provenance.
- _3 value "In fact, Skp2 overexpression was shown to induce the transcription of c-Myc target genes suggesting that Skp2 acts as a transcription coactivator of c-Myc. Skp2 can concurrently lead to degradation of tumor suppressors (p27, p57, p21 and p130) and to activation of an oncogene (c-Myc). While Skp2-deficient mice, which should have decreased c-Myc activity, can develop almost normally" provenance.
- _3 value "In fact, Skp2 overexpression was shown to induce the transcription of c-Myc target genes suggesting that Skp2 acts as a transcription coactivator of c-Myc. Skp2 can concurrently lead to degradation of tumor suppressors (p27, p57, p21 and p130) and to activation of an oncogene (c-Myc). While Skp2-deficient mice, which should have decreased c-Myc activity, can develop almost normally" provenance.
- _3 value "In fact, Skp2 overexpression was shown to induce the transcription of c-Myc target genes suggesting that Skp2 acts as a transcription coactivator of c-Myc. Skp2 can concurrently lead to degradation of tumor suppressors (p27, p57, p21 and p130) and to activation of an oncogene (c-Myc). While Skp2-deficient mice, which should have decreased c-Myc activity, can develop almost normally" provenance.