Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RAjOg_6KYg5uorI0OHvZk0UDmZn3F0U0-oywA1dDMn6iA#_3> ?p ?o ?g. }
Showing items 1 to 2 of
2
with 100 items per page.
- _3 value "In fact, Skp2 overexpression was shown to induce the transcription of c-Myc target genes suggesting that Skp2 acts as a transcription coactivator of c-Myc. Skp2 can concurrently lead to degradation of tumor suppressors (p27, p57, p21 and p130) and to activation of an oncogene (c-Myc). While Skp2-deficient mice, which should have decreased c-Myc activity, can develop almost normally" provenance.
- _3 wasQuotedFrom 15021891 provenance.