Matches in Nanopublications for { ?s ?p "Overexpression of SHIP2 blocks hypertrophy in muscle [6,7]. Expression of a dominant-negative mutant form of SHIP2 (dnSHIP2), in which the phosphatase has been rendered inactive, enables Akt1 to remain active by blocking the dephosphorylation of PtdIns(3,4,5)P3 [37]. Expression of dnSHIP2 in myotubes causes hypertrophy, coincident with an increase in the levels of phosphorylated Akt1 [6]." ?g. }
Showing items 1 to 1 of
1
with 100 items per page.
- _4 value "Overexpression of SHIP2 blocks hypertrophy in muscle [6,7]. Expression of a dominant-negative mutant form of SHIP2 (dnSHIP2), in which the phosphatase has been rendered inactive, enables Akt1 to remain active by blocking the dephosphorylation of PtdIns(3,4,5)P3 [37]. Expression of dnSHIP2 in myotubes causes hypertrophy, coincident with an increase in the levels of phosphorylated Akt1 [6]." provenance.