Matches in Nanopublications for { ?s ?p "The PI3K pathway is negatively regulated by PTEN (phosphatase and TENsin homolog), which converts PIP3 in PIP2, preventing PKB activation and Bad phosphorylation/sequestration. Thus PTEN is considered as a tumor suppressor gene. It has been shown that NS-398 was able to increase the level of PTEN in human gastric carcinoma cell line MKN45 [114]. " ?g. }
Showing items 1 to 1 of
1
with 100 items per page.
- _5 value "The PI3K pathway is negatively regulated by PTEN (phosphatase and TENsin homolog), which converts PIP3 in PIP2, preventing PKB activation and Bad phosphorylation/sequestration. Thus PTEN is considered as a tumor suppressor gene. It has been shown that NS-398 was able to increase the level of PTEN in human gastric carcinoma cell line MKN45 [114]. " provenance.