Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence Enhanced+performance+in+the+spatial+learning+task+is+associated+with+a+higher+expression+of+zif268+in+the+CA3%2FCA4+region+of+the+hippocampus. assertion.
- assertion asSentence EGR-1+decoy+ODNs+inhibit+vascular+smooth+muscle+cell+proliferation+and+neointimal+hyperplasia+of+balloon-injured+arteries+in+rat. assertion.
- assertion asSentence Long-term+ethanol+feeding+promoted+steatosis+and+fibrosis+in+LE+rats+via+EGR1+activation. assertion.
- assertion asSentence Atf3+is+a+nexus+in+cardiomyocyte+hypertrophy+required+to+facilitate+the+full+and+proper+cell+growth+response. assertion.
- assertion asSentence The+antioxidant+Trolox+attenuates+mechanical+ventilation-induced+diaphragmatic+atrophy+independent+of+alterations+in+Akt+regulation+of+FoxO+transcription+factors+and+expression+of+MAFbx+or+MuRF-1. assertion.
- assertion asSentence GAPDH+plays+a+significant+role+in+the+development+of+diabetic+retinopathy+and+its+progression+after+cessation+of+hyperglycemia. assertion.
- assertion asSentence Postsynaptic+localization+of+sst%281%29+receptors+and+synaptic+connectivity+in+the+ARC+undergo+pronounced+remodeling+in+parallel+with+the+GH+rhythm. assertion.
- assertion asSentence Hrs+and+Tsg101+as+crucial+regulators+of+trafficking+of+Cx43+to+lysosomes. assertion.
- assertion asSentence Changes+in+Cx43+expression+following+engraftment+of+neural+stem+cells+to+striatal+tissue. assertion.
- assertion asSentence Fixed+spaced+electrical+shock+to+spinal+cord+transected+rats+engages+a+form+of+NMDA+receptor-mediated+plasticity. assertion.
- assertion asSentence Developmental+change+in+the+synaptic+surface+content+of+NR2A+and+NR2B+subunits+correlates+with+a+developmental+change+in+the+time+spent+by+the+subunits+within+synapses. assertion.
- assertion asSentence NR1%2FNR2B%2FNR2D+triheteromers+form+a+significant+fraction+of+synaptic+NMDA+receptors+during+postnatal+development+in+dopaminergic+neurones+of+the+substantia+nigra+pars+compacta. assertion.
- assertion asSentence Exposure+to+oxygen-glucose+deprivation+in+organotypic+hippocampal+slices+prepared+from+4-day-old+and+7-day-old+rat+pups+is+associated+with+a+transition+in+N-methyl-D-aspartate+receptor+subunit+composition+from+NR2B+type+predominant+to+NR2A+predominant. assertion.
- assertion asSentence Activity-dependent+changes+in+the+NR2A%2FNR2B+ratio+take+an+active+role+in+bidirectional+metaplastic+regulation+of+the+long-term+potentiation%2Flong-term+depression+%28LTP%2FLTD%29+threshold. assertion.
- assertion asSentence Glucocorticoid+receptors+and+CRF-2+receptors+participate+in+the+CRF-induced+analgesic+effect. assertion.
- assertion asSentence Resting+sympathetic+vasomotor+tone+is+maintained+by+tonic+activation+of+group+I+mGluRs+in+the+paraventricular+nucleus+in+hypertension. assertion.
- assertion asSentence Activation+of+a+group+III+mGluR+in+bone+marrow+stromal+cells+inhibits+a+Ca%282%2B%29-permeable+plasma+membrane+channel%2C+reducing+%5BCa%282%2B%29%5D%28i%29+and+suppressing+generation+of+NO. assertion.
- assertion asSentence Type-5+metabotropic+glutamate+receptor+%28mGluR5%29-positive+allosteric+modulators+affect+the+extinction+of+cocaine-seeking+behavior+in+rats+with+a+history+of+intravenous+cocaine+self-administration. assertion.
- assertion asSentence PHCCC+directly+activates+the+mGlu%286%29+receptor+and+does+not+enhance+activity+of+glutamate. assertion.
- assertion asSentence Endogenous+HGF+overexpression+is+responsible+for+suppression+of+glycerol-induced+tubular+apoptosis+after+partial+hepatectomy. assertion.
- assertion asSentence Exposure+to+diesel+exhaust+particles+elevated+transcription+of+heme+oxygenase-1+gene+in+rat+alveolar+macrophages. assertion.
- assertion asSentence HO-1+plays+an+important+role+in+protecting+the+gut+against+I%2FR-induced+injury. assertion.
- assertion asSentence HO-1+ameliorates+ischemia%2Freperfusion+injury+by+targeting+dendritic+cell+maturation+and+migration. assertion.
- assertion asSentence Nrf2-mediated+HO-1+induction+confers+adaptive+survival+response+to+tetrahydropapaveroline-induced+oxidative+PC12+cell+death. assertion.
- assertion asSentence Pulmonary+embolism+that+causes+pulmonary+hypertension+is+associated+with+haptoglobin+depletion+and+up-regulation+of+HMOX1+enzyme. assertion.
- assertion asSentence Upregulation+of+heme+oxygenase-1+inhibits+the+maturation+and+mineralization+of+osteoblasts. assertion.
- assertion asSentence Glutamine+pretreatment+significantly+ameliorates+the+LPS-induced+expression+of+HO-1+in+intestinal+tissue. assertion.
- assertion asSentence Extracellular+HSC70+plays+a+critical+role+in+regulating+the+myocardial+innate+immune+response+and+cardiac+function+after+ischemia-reperfusion. assertion.
- assertion asSentence A+sequential+mechanism+for+clathrin+cage+disassembly+by+70-kDa+heat-shock+cognate+protein+%28Hsc70%29+and+auxilin. assertion.
- assertion asSentence Administration+of+brain-derived+neurotrophic+factor+suppresses+the+expression+of+heat+shock+protein+27+in+rat+retinal+ganglion+cells+following+axotomy. assertion.
- assertion asSentence Ginseng+has+a+protective+effect+against+ethanol-induced+gastric+damages+by+induction+of+heat-shock+proteins+70+and+27. assertion.
- assertion asSentence The+inability+of+IAPP+to+self+assemble+can+be+ascribed%2C+in+part%2C+to+several+slowly+exchanging+conformations+evident+as+multiple+chemical+shift+assignments+in+the+immediate+vicinity+of+three+proline+residues+residing+outside+of+this+helical+region. assertion.
- assertion asSentence Long-term+protection+of+pro-oligodendroblasts+by+IGF-I+correlates+with+sustained+activation+of+Akt+and+protects+immature+oligodendrocytes+from+glutamate-mediated+apoptosis. assertion.
- assertion asSentence IGF-1-mediated+vasodilatory+response+is+not+mediated+by+the+CGRP-dependent+perivascular+neurons. assertion.
- assertion asSentence Normal+IL-1+signaling+is+required+for+the+production+of+brain+PGE%282%29+under+basal+conditions+and+in+response+to+surgical+stress. assertion.
- assertion asSentence TNF-alpha+or+IL-1+beta+both+induce+acute+changes+in+the+peritoneum+that+mimic+those+seen+in+peritoneal+dialysis+patients+who+experience+an+episode+of+peritonitis. assertion.
- assertion asSentence Inflammatory+cytokines+%28Il-6%2C+Il-1beta%2C+TNFalpha%29+can+significantly+reduce+dendrite+development+and+complexity+of+developing+cortical+neurons%2C+consistent+with+the+neuropathology+of+schizophrenia. assertion.
- assertion asSentence Examine+particle-induced+Il1beta+responses+in+cardiac+cell+cultures--the+effect+of+particles+versus+soluble+mediators+released+by+particle-exposed+lung+cells. assertion.
- assertion asSentence NF+kappa+B+pathway+is+involved+in+the+transcriptional+regulation+of+the+TNF-alpha+and+IL-6+overexpression+in+primary+Substance+P-stimulated+mast+cells. assertion.
- assertion asSentence FSH+up+%281.4-fold%29+regulates+the+levels+of+expression+of+IL-6+mRNA+only+in+the+immature+rat+Sertoli+cells. assertion.
- assertion asSentence LPS+promotes+cholangiocyte+proliferation+through+the+IL-6%2FSTAT3+pathway. assertion.
- assertion asSentence Adiponectin+enhances+IL-6+synthesis+and+release+in+adult+rat+cardiac+fibroblasts+through+AdipoR1. assertion.
- assertion asSentence Activation+of+a+pro-survival+IL-6%2FJAK2%2FSTAT3+cascade+contributes+to+cholera+toxin-induced+GFAP+expression. assertion.
- assertion asSentence Insulin+depletion+and+hyperglycemia+do+not+regulate+the+expression+of+GLUT8+in+testes. assertion.
- assertion asSentence Insulin+%28Ins%29+release+is+altered+by+anesthetics. assertion.
- assertion asSentence Both+endospanins+are+regulators+of+postinternalization+membrane+traffic+of+the+endocytic+pathway+of+OB-R. assertion.
- assertion asSentence Mbp+is+a+binding+partner+and+calmodulin+adaptor+for+the+BKCa+channel. assertion.
- assertion asSentence Myelin+basic+protein-reactive+T+cells+persist+in+an+inactive+state+in+the+bone+marrow+of+Lewis+rats+that+have+recovered+from+autoimmune+encephalomyelitis. assertion.
- assertion asSentence There+is+a+%3E10-fold+increase+in+expression+of+Mt1a+at+night+in+the+rat+pineal+gland. assertion.
- assertion asSentence C-Myc+and+phosphorylated+ERK1%2F2+play+important+roles+in+transforming+growth+factor+beta-1+promotion+of+cell+proliferation+and+cell+cycle+progression+in+rat+nucleus+pulposus+cell+cultures. assertion.
- assertion asSentence Loss+or+inactivation+of+the+polysialyl+tail+of+NCAM+reduces+the+migration+of+mechanically+wounded+oligodendrocyte+progenitor-like+%28O-2A%29+cells+into+the+injured+area+and+completely+blocks+the+wound+closure. assertion.
- assertion asSentence Androgen+regulation+of+amyloid+beta+%28Abeta%29protein+involves+an+androgen+receptor-dependent+mechanism+requiring+up-regulation+of+Abeta+catabolizing+enzyme+neprilysin. assertion.
- assertion asSentence Ovariectomy+increases+BACE1+expression+and+decreases+neprilysin+expression+in+hippocampus. assertion.
- assertion asSentence NGF+administration+reverses+the+neuro-glial+morphomolecular+changes+occurring+in+neuropathic+animals+paralleled+by+alterations+in+neurotrophin+receptors+ratio. assertion.
- assertion asSentence Neuronal+nitric+oxide+synthase+is+critical+to+transmission+of+baroreflex+signals+through+the+nucleus+tractus+solitarii. assertion.
- assertion asSentence Differential+expression+of+nNOS+mRNA+is+found+in+the+solitary+nucleus+of+young+and+aged+Wistar-Kyoto+and+spontaneously+hypersensitive+rats. assertion.
- assertion asSentence Hsp27+inhibited+NOS+gene+expression+in+motoneuron+after+avulsion. assertion.
- assertion asSentence After+tourniquet+application+to+a+hind+limb%2C+iNOS+mRNA+expression+is+rapidly+up-regulated+in+rat+dorsal+root+ganglion. assertion.
- assertion asSentence Intra-hippocampal+injections+of+the+iNOS+inhibitor+aminoguanidine+during+chronic+unexpected+mild+stress+%28CUMS%29+suppressed+CUMS-induced+depression-like+behavioral+changes. assertion.
- assertion asSentence iNOS+expression+in+the+rostral+ventrolateral+medulla+of+spontaneously+hypertensive+rats+contributes+to+increase+blood+pressure. assertion.
- assertion asSentence Angiotensin+II+via+angiotensin+II+type+1+receptor+increases+the+accumulation+of+neutrophils+and+iNOS+expression+and+plays+a+significant+role+in+mediating+inflammation+in+gastric+mucosa+exposed+to+ischemia-reperfusion. assertion.
- assertion asSentence Vascular+smooth+muscle+cells+express+NOD1+receptors+and+respond+to+agonists+by+expressing+increased+NOS2. assertion.
- assertion asSentence Induction+of+iNOS+and+nitric+oxide+production+are+closely+associated+with+transglutaminase+2+expression. assertion.
- assertion asSentence Methylargines+through+eNos+are+critical+mediators+of+vascular+dysfunction+following+vascular+injury. assertion.
- assertion asSentence Endogenous+11+beta-HSD1+and+11+beta-HSD2+play+significant+and+distinct+roles+in+modulating+the+effect+of+glucocorticoids+on+eNOS+expression. assertion.
- assertion asSentence Neonatal+oxytocin+treatment+modulates+ANP+in+rat+heart. assertion.
- assertion asSentence Enhanced+NPY+content+and+vasoconstriction+to+NPY+in+arteries+from+hypertensive+rats+can+contribute+to+the+enhanced+sympathetic+nerve+activity+and+vascular+resistance+in+female+hypertensive+rats. assertion.
- assertion asSentence Glucocorticoids+increase+neuropeptide+Y+and+agouti-related+peptide+gene+expression+via+adenosine+monophosphate-activated+protein+kinase+signaling+in+the+arcuate+nucleus. assertion.
- assertion asSentence Intrinsic+cardiac+adrenergic+cells+constitute+a+delta-opioid-regulated+adrenopeptidergic+paracrine+system+conferring+robust+cardioprotection+through+beta%282%29-AR%2FCGRP-R+co-signalling. assertion.
- assertion asSentence Orm1+gene+expression+highly+induced+in+cardiomyocytes+overexpressing+mineralocorticoid+receptor+and+treated+with+aldosterone. assertion.
- assertion asSentence Increased+PDE4+activity%2C+specifically+phosphodiesterase+4B4+activity%2C+reduces+beta-adrenergic+signaling+in+the+kidney+and+contributes+to+salt-sensitive+hypertension+in+the+Dahl+SS+rat. assertion.
- assertion asSentence Nucleostemin+expression+in+cardiomyocytes+is+induced+by+fibroblast+growth+factor-2+and+accumulates+in+response+to+Pim-1+kinase+activity. assertion.
- assertion asSentence Melanin-concentrating+hormone+is+expressed+in+the+laterodorsal+tegmental+nucleus+only+in+female+rats. assertion.
- assertion asSentence Role+as+neuroendocrine+mediator+of+effects+of+estrogens. assertion.
- assertion asSentence POMC+peptides+are+not+required+for+prenatal+adrenal+development+nor+for+postnatal+differentiation. assertion.
- assertion asSentence Estrogen+differentially+regulates+expression+of+the+PRL-R+mRNA+in+the+different+brain+regions+by+increasing+the+utilization+of+PRL-R+gene+promoters+1A+and+1C+in+the+female+rat. assertion.
- assertion asSentence Expression+of+PRLR+gene+in+the+female+and+male+rat+brains+increases+during+postnatal+development+due+to+the+transcriptional+activation+of+the+E1%284%29+first+exon. assertion.
- assertion asSentence The+down-regulation+of+Parathyroid+hormone-related+peptide+favours+atherosclerosis+in+chronic+pressure+overload. assertion.
- assertion asSentence CD45+acts+as+a+negative+regulator+of+cytokine+production. assertion.
- assertion asSentence Medial+prefrontal+cortex+reelin+signaling+plays+an+important+role+in+behavioral+tasks+with+relevance+to+schizophrenia%2C+for+example. assertion.
- assertion asSentence AKAP15+directly+interacts+with+Na%28v%291.2a+channels+via+the+intracellular+loop+between+domains+I+and+II. assertion.
- assertion asSentence Rac1-mediated+NOX2+activity+is+an+important+component+in+O%282%29%28-%29+regulation+of+ENaC. assertion.
- assertion asSentence TNF-alpha-stimulated+CCL2%2FMCP-1+production+in+rat+VSMCs+is+dually+regulated+by+activator+protein-1+%28AP-1%29+and+NF-kappaB+pathways. assertion.
- assertion asSentence Expression+of+the+proteoglycan+syndecan-4+and+the+mechanism+by+which+it+mediates+stress+fiber+formation+in+folliculostellate+cells+in+the+rat+anterior+pituitary+gland. assertion.
- assertion asSentence There+is+a+significantly+higher+level+of+the+Shbg+transcript+in+hypodactylous+rats+compared+to+SHR+controls. assertion.
- assertion asSentence ANG+II+stimulates+NHE3+via+AT1R-PLC-CaM+pathway+and+inhibits+NHE3+by+AT1R-PKG+activation. assertion.
- assertion asSentence Using+gastrocnemius+muscles+of+mice+overexpressing+human+mutant+SOD1+%28mutSOD1%29+at+different+disease+stages. assertion.
- assertion asSentence Vesicle-associated+membrane+protein+2+is+involved+in+secretion+of+polypeptides+from+the+choroid+plexus+epithelium. assertion.
- assertion asSentence Immunoreactive+substance+P+is+not+part+of+the+retinohypothalamic+tract+in+the+rat. assertion.
- assertion asSentence In+the+solitary+nucleus%2C+the+relative+densities+of+substance+P+and+NK1+receptors+varied+in+parallel+across+subnuclei%2C+with+both+being+moderate+to+dense+in+the+dorsocentral%2C+chemoresponsive+zone. assertion.
- assertion asSentence NK3R+signaling+in+magnocellular+neurons+has+a+critical+role+for+the+release+of+VP+and+OT+in+response+to+hypotension. assertion.
- assertion asSentence Insulin+potentiates+endothelin-1+elicited+vessel+contractile+responses+via+thromboxane+A2+receptor+signaling. assertion.
- assertion asSentence Post-transcriptional+mechanisms+are+responsible+for+the+up-regulation+of+TP+receptor+by+lipid+soluble+smoke+particles%2C+in+which+enhanced+translation+is+the+major+cause+of+the+elevated+protein+expression+and+the+enhanced+contraction. assertion.
- assertion asSentence Transcriptional+down-regulation+of+thromboxane+A%282%29+receptor+expression+via+activation+of+MAPK+ERK1%2F2%2C+p38%2FNF-kappaB+pathways. assertion.
- assertion asSentence TNF-alpha+plays+a+significant+role+in+the+tissue+specificity+and+signal+selectivity+of+insulin+resistance. assertion.
- assertion asSentence In+the+initiation+phase+of+pulmonary+oxygen+toxicity%2C+an+increase+of+TNFalpha+and+its+receptor+TNFR1+leads+to+the+activation+of+caspase+8+and+3+in+TIIcells. assertion.
- assertion asSentence In+vivo+chronic+TNF-alpha+inhibition+improves+flow-mediated+arterial+dilation+in+resistance+arteries+of+aged+female+animals. assertion.
- assertion asSentence STAT1+ASON+can+inhibit+the+secretion+of+TNF-alpha%2C+IL-8+and+NO+in+AMs. assertion.
- assertion asSentence Expression+modulated+in+apoptotic+hepatocytes+during+Candida+albicans+infection. assertion.
- assertion asSentence TNF-alpha+contributes+to+the+increase+in+renal+inflammation+in+DOCA-salt+rats. assertion.