Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence Intrinsic+sensitivity+of+Kir1.1+%28ROMK%29+to+glibenclamide+in+the+absence+of+SUR2B. assertion.
- assertion asSentence TFF3+contributes+to+the+malignant+behavior+of+colon+cancer+cells. assertion.
- assertion asSentence AgRP+and+NPY+mRNA+levels+in+similar+arcuate+nucleus+neurons+are+differentially+regulated+following+a+stressful+event. assertion.
- assertion asSentence Amino+acids+can+act+within+the+brain+to+inhibit+food+intake+via+a+direct%2C+mTOR-dependent+inhibition+of+Agrp+gene+expression. assertion.
- assertion asSentence Transferable+factor%28s%29+mediate+the+ischemia-reperfusion+injury-induced+decrease+in+NHE3+of+the+kidney. assertion.
- assertion asSentence Expression+of+all+4+members+of+the+Id+family+of+transcription+factors+is+differentially+regulated+in+response+to+orchidectomy+along+the+epididymis. assertion.
- assertion asSentence Agrn+becomes+concentrated+at+neuroeffector+and+neuromuscular+juncions+in+developing+urinary+bladder. assertion.
- assertion asSentence Conjugated+linoleic+acid+can+improve+insulin+resistance+of+obese+rat+and+increase+the+expression+of+fatty+acid+binding+protein+2+mRNA. assertion.
- assertion asSentence Mu+opioid+receptors+are+in+discrete+hippocampal+interneuron+subpopulations. assertion.
- assertion asSentence Mu+receptors+participate+in+maintaining+normal+morphology+and+function+of+dendritic+spines+in+neuros. assertion.
- assertion asSentence RGS4+plays+a+key+role+in+G+protein+coupling+selectivity+and+signaling+of+the+mu-+and+delta-opioid+receptors. assertion.
- assertion asSentence Mu+and+delta+receptors+in+the+anteroventral+preoptic+region+are+involved+in+the+increase+of+body+temperature+during+normoxia+post-hypoxia. assertion.
- assertion asSentence Orexin+Stimulation+of+amylase+release+by+a+pancreatic+cell+line+is+mediated+by+Orexin+2+receptors. assertion.
- assertion asSentence Examine+the+role+of+hcrtR2+in+nicotine%27s+reinforcing+effects. assertion.
- assertion asSentence Resting+and+circadian+release+of+nitric+oxide+is+controlled+by+leptin+in+male+rats. assertion.
- assertion asSentence Parallel+decreases+in+serum+leptin+and+skeletal+muscle+enzyme+activities+with+energy+restriction-induced+intra-abdominal+adipose+reduction. assertion.
- assertion asSentence TGFbeta+also+modulates+FAK+protein+levels+in+cultured+rat+IEC-6+intestinal+epithelial+cells+via+ERK+activation. assertion.
- assertion asSentence Role+of+TINag+in+cell+survival+utilizing+integrin+%28alpha%29vbeta3%2Ffocal+adhesion+kinase+%28FAK%29%2Fphosphatidylinositol+3-kinase+%28PI3K%29%2Fprotein+kinase+B-serine%2Fthreonine+kinase+%28AKT%29+signaling+pathway. assertion.
- assertion asSentence Up-regulation+of+GRP78+induced+by+2DG+counteracts+primary+cellular+damage+in+fetal+rat+cerebral+neurons+caused+by+endoplasmic+reticulum+stress+in+utero. assertion.
- assertion asSentence BDNF-+and+seizure-dependent+phosphorylation+of+STAT3+cause+the+adenosine+3%27%2C5%27-monophosphate+%28cAMP%29+response+element-binding+protein+%28CREB%29+family+member+ICER+%28inducible+cAMP+early+repressor%29+to+bind+with+phosphorylated+CREB+at+the+Gabra1%3ACRE+site. assertion.
- assertion asSentence ROS-mediated+oxidation+of+SHP-2+is+essential+for+the+hUII-induced+mitogenic+pathway+in+NRK-52E+cells. assertion.
- assertion asSentence Glucocorticoid+suppresses+BDNF-stimulated+MAPK%2FERK+pathway+via+inhibiting+interaction+of+Shp2+with+TrkB. assertion.
- assertion asSentence ST6Gal-I+regulates+macrophage+apoptosis+via+alpha2-6+sialylation+of+the+TNFR1+death+receptor. assertion.
- assertion asSentence Smad3+and+Pitx2+cooperate+in+stimulation+of+FSHbeta+gene+transcription. assertion.
- assertion asSentence TGF-beta1+exerts+bi-directional+regulation+on+fibroblast+proliferation+by+modulating+Smad3+activity. assertion.
- assertion asSentence TGF-beta1+treatment+increases+expression+of+Smad3+in+myocardial+hypertrophy. assertion.
- assertion asSentence Notch+induces+myofibroblast+differentiation+of+alveolar+epithelial+cells+via+transforming+growth+factor-%7Bbeta%7D-Smad3+pathway. assertion.
- assertion asSentence PKA+and+Epac+cooperatively+enhance+functional+GJ+neoformation+in+cardiomyocytes. assertion.
- assertion asSentence The+effect+of+hepcidin+in+reducing+transferrin+receptor+1+expression+is+dependent+on+the+cyclic+AMP-protein+kinase+A+pathway%2C+a+primary+and+dominant+event+essential+for+brain+homeostasis. assertion.
- assertion asSentence 15d-PGJ%282%29+exerts+its+anti-inflammatory+effect+in+rat+chondrocytes+by+a+PPARgamma-independent+mechanism. assertion.
- assertion asSentence PPAR-gamma+activator+rosiglitazone+attenuated+Ang+II-induced+blood+pressure+elevation+and+intracellular+signaling+on+aorta+and+mesenteric+vessels. assertion.
- assertion asSentence Activation+of+PPAR+gamma+can+modulate+pro-fibrotic+and+pro-inflammatory+roles+of+hepatic+stellate+cells. assertion.
- assertion asSentence The+Necdin-Wnt+pathway+causes+epigenetic+peroxisome+proliferator-activated+receptor+gamma+repression+in+hepatic+stellate+cells. assertion.
- assertion asSentence After+apoptosis+induction+calcium+permeability+of+the+nuclear+calcium+store+vesicles+increases+via+IP%283%29+receptor+translocation+to+nucleus. assertion.
- assertion asSentence The+gene+coding+for+the+5-HT+5A+receptor+is+already+active+in+the+embryonic+rat+brain+and+is+differentially+expressed+during+development. assertion.
- assertion asSentence Ahr+is+present+in+luminal+endothelial+cells+of+the+rat+aorta. assertion.
- assertion asSentence Insulin-degrading+enzyme+rapidly+removes+the+beta-amyloid+precursor+protein+intracellular+domain+%28AICD%29. assertion.
- assertion asSentence CNTF+promotes+the+outgrowth+of+embryonic+cranial+motor+neurons+in+isolated+stage+E12+hindbrain+explants. assertion.
- assertion asSentence Three-dimensional+reconstructions+of+CNTF-immunoreactive+axonal+bulbar+projections+of+these+neurons+revealed+an+ordered+bilaterally+symmetric+pattern. assertion.
- assertion asSentence UCP3+attenuates+endogenous+radical+production+by+the+mitochondrial+electron+transport+chain+at+high+protonmotive+force. assertion.
- assertion asSentence Circadian+expression+of+interferon+gamma+mRNA+is+demonstrated+for+the+first+time+in+natural+killer+%28NK%29+cells+enriched+from+rat+spleen. assertion.
- assertion asSentence Tgfbeta3+mRNA+is+primarily+increased+in+the+sciatic+nerve+in+rats+with+streptozotocin+diabetic+neuropathy. assertion.
- assertion asSentence HEB+is+implicated+in+the+development+of+skeletal+muscle+%28HEB%29. assertion.
- assertion asSentence Orexin-A+and+orexin-B+play+an+important+role+in+the+early+postnatal+brain+development. assertion.
- assertion asSentence ApoE-containing+astrocyte+lipoproteins+exhibit+the+most+robust+interactions+with+Abeta. assertion.
- assertion asSentence Kv2.1+clusters+are+strategically+situated+at+neuroglial+junctions+to+achieve+the+rapid+modulation+after+ischemic+stress+via+glutamate+signaling. assertion.
- assertion asSentence Glucose+metabolism+regulates+Kv2.1+channels+in+rats+beta-cells+via+altering+MgATP+levels. assertion.
- assertion asSentence The+pleckstrin+homology+domain+of+Plcg1+interacts+with+human+insulin+receptor. assertion.
- assertion asSentence Transfection+of+phosphatidylethanolamine+N-methyltransferase+2+gene+can+inhibit+the+phosphorylation+and+translocation+from+cytosol+to+plasma+membrane+of+PLC+gamma+1. assertion.
- assertion asSentence Simplexvirus-mediated+overexpression+of+PLCgamma1+in+PC12+cells+induced+ERK+activation+via+a+mechanism+dependent+on+protein+kinases. assertion.
- assertion asSentence An+endogenous+receptor-mediated+signaling+process+in+pancreatic+beta-cells+is+dependent+on+G+alpha%28z%29+function. assertion.
- assertion asSentence Addition+of+non-ionic+detergent+allowed+whole+capping+protein+to+bind+weakly+to+S100B%2C+so+the+alpha-subunit+C+terminus+can+be+mobilized+from+the+surface+of+the+capping+protein+molecule%2C+by+weakening+the+hydrophobic+binding+at+the+contact+site. assertion.
- assertion asSentence Ppara-mediated+metabolic+remodeling+of+skeletal+myocytes+mimics+exercise+training+and+reverses+lipid-induced+mitochondrial+ineficiency. assertion.
- assertion asSentence MAOB+is+involved+in+the+inactivation+mechanism+of+histamine+that+is+released+from+ECL+cells+and+activates+parietal+cells+to+secrete+gastric+acid. assertion.
- assertion asSentence Localization+of+dynamin+2+in+rat+seminiferous+tubules+during+the+spermatogenic+cycle. assertion.
- assertion asSentence Immunohistochemistry+of+the+cerebellum+from+3-month-old+rats+demonstrates+that+lobules+1-8+are+distinct+from+lobules+9+and+10+with+respect+to+localization+of+NB-3+protein. assertion.
- assertion asSentence D-amino+acid+oxidase+activity+is+inhibited+by+an+interaction+with+bassoon+protein+at+the+presynaptic+active+zone. assertion.
- assertion asSentence Low-grade+chronic+inflammation+after+an+acute+initial+insult+causes+a+persistent+increase+in+the+expression+of+galanin+in+the+mucosa. assertion.
- assertion asSentence Over-expression+of+calpastatin+inhibits+calpain+activation+and+improves+myocardial+function+in+endotoxaemia. assertion.
- assertion asSentence Caveolin-3+plays+an+important+role+in+the+mechanism+by+which+17+beta-estadiol+attenuates+diet-induced+glucose+intolerance. assertion.
- assertion asSentence Glucagon+induces+protein+kinase+A+and+microtubule-dependent+translocation+of+AQP8+water+channels+to+hepatocyte+canalicular+plasma+membrane%2C+leading+to+increase+in+membrane+water+permeability. assertion.
- assertion asSentence A+defective+expression+of+canalicular+AQP8+contributes+as+a+mechanism+for+bile+secretory+dysfunction+of+cholestatic+hepatocytes. assertion.
- assertion asSentence PB-cadherin+promotes+survival+of+spermatocytes+and+activates+Jak2+and+Stat3+signalling. assertion.
- assertion asSentence Transgenic+expression+of+Cd36+plays+an+important+role+in+modulating+the+incidence+and+severity+of+ischemic+and+reperfusion+ventricular+arrhythmias+and+myocardial+infarct+size+induced+by+coronary+artery+occlusion. assertion.
- assertion asSentence Stimulation+of+activin+A+expression+in+rat+aortic+smooth+muscle+cells+by+thrombin+and+angiotensin+II+correlates+with+neointimal+formation+in+vivo+following+vascular+injury. assertion.
- assertion asSentence Activin+beta%28A%29+gene+activation+is+mediated+by+a+calcuim%2Fcalmodulin+pathway+in+RBL-2H3+mast+cells. assertion.
- assertion asSentence There+is+AT%281A%29R-+and+insulin-mediated+competitive+signaling+cross+talk+to+regulate+megalin+expression+in+cultured+proximal+tubule+cells. assertion.
- assertion asSentence Predominant+neuritic+pathology+induced+by+viral+overexpression+of+alpha-synuclein+in+cell+culture. assertion.
- assertion asSentence The+upregulation+of+the+arginase+expression+in+wound+derived+fibroblasts+underlines+the+distinct+regulation+of+l-arginine+metabolism+in+WFBs. assertion.
- assertion asSentence The+highest+affinity+inhibitorsof+Arg1+displace+the+metal-bridging+hydroxide+ion+%28and+sometimes+occupy+a+Mn%282%2B%29%28A%29+site+found+vacant+in+the+native+enzyme%29+and+maintain+a+conserved+array+of+hydrogen+bonds+with+their+alpha-amino+and+-carboxylate+groups. assertion.
- assertion asSentence Activation+of+ORL-1+receptors+on+myenteric+neurons+by+nociceptin+reduces+excitatory+and+inhibitory+neurotransmission+within+the+gastrointestinal+tract+to+alter+peristalsis. assertion.
- assertion asSentence Iris+tissue+macrophages+expressed+TLR4+during+endotoxin-induced+uveitis. assertion.
- assertion asSentence Coronin+2A+and+cofilin+regulate+a+subset+of+focal-adhesion-turnover+events. assertion.
- assertion asSentence Intravenously+injected+uridine+or+cytidine+is+able+to+decrease+arterial+pressure+by+activating+peripheral+A1%2FA2A+adenosine+receptors. assertion.
- assertion asSentence Simvastatin+restores+down-regulated+GATA-6+expression+in+pulmonary+hypertensive+rats. assertion.
- assertion asSentence Load-dependent+maintenance+or+upregulation+of+the+nucleolar+number+and%2For+phosphorylation+of+S6+and+HSP27+plays+the+important+role%28s%29+in+the+regulation+of+skeletal+muscle+mass. assertion.
- assertion asSentence Endogenously+produced+luminal+surface+adenosine+increases+HCO3-+secretion+in+an+intact+intestinal+epithelium+in+vivo+through+the+activation+of+A2B+receptors. assertion.
- assertion asSentence Peroxiredoxin+2+is+an+important+modulator+of+angiotensin+II-induced+podocyte+injury. assertion.
- assertion asSentence Prdx+2+expression+in+perinatal+rat+brain+remained+largely+unchanged. assertion.
- assertion asSentence Direct+effect+of+hypoxia+on+epigenetic+modification+of+DNA+methylation+and+programming+of+cardiac+PKCepsilon+gene+repression+in+a+sex-dependent+manner. assertion.
- assertion asSentence During+postnatal+development+of+the+hippocampus%2C+the+spatio-temporal+expression+of+FAAH+correlates+well+with+the+general+pattern+of+neuronal+maturation. assertion.
- assertion asSentence Neuropeptide+Y1+receptor+is+exclusively+expressed+by+Purkinje+cells+in+the+cerebellum+during+postnatal+development. assertion.
- assertion asSentence Via+a+specific+Y-1R%2FY-5R+interplay%2C+NPY+acts+as+a+neuroimmune+co-transmitter+in+vivo. assertion.
- assertion asSentence Diabetes+is+associated+with+an+abnormal+BMP%2FMAD+homolog+Smad+signaling+expression+in+the+myenteric+ganglia+that+affects+the+homeostasis+of+the+enteric+plexus. assertion.
- assertion asSentence IRS-2+in+osteoblast+is+up-regulated+by+E2+and+plays+important+roles+in+the+estrogen-+induced+bone+formation. assertion.
- assertion asSentence A+very+clear+presence+of+MeCP2+protein+is+found+in+oligodendrocyte+progenitors+isolated+from+neonatal+rat+brain. assertion.
- assertion asSentence The+early+post-hypoxic+up-regulation+of+BACE1+depends+on+the+production+of+reactive+oxygen+species+mediated+by+the+sudden+interruption+of+the+mitochondrial+electron+transport+chain. assertion.
- assertion asSentence Enteropeptidase+is+a+BACE1+substrate+in+vivo. assertion.
- assertion asSentence The+expression+of+Eotaxin+in+nasal+lavage+fluid+and+nasal+mucosa+increased+after+treatment+of+allergic+rhinitis+with+histamine. assertion.
- assertion asSentence Expression+of+alpha1-adrenoceptors+on+C-+and+delta-nociceptive+afferent+fibers+provides+a+histochemical+substrate+for+direct+excitation+of+these+fibers+by+adrenergic+agonists. assertion.
- assertion asSentence Chondroitinase+ABC+can+enhance+the+expression+of+GAP-43+after+spinal+cord+injury. assertion.
- assertion asSentence Ttrahydroxystilbene+glucoside+can+improve+the+neurological+function+through+increasing+the+expressions+of+NGF+and+GAP-43+of+cerebral+ischemia-reperfusion+rats. assertion.
- assertion asSentence Effects+of+LPS+on+quiescent+hepatic+stellate+cells+are+novel%2C+occurring+without+the+aid+of+LBP%2FCD14. assertion.
- assertion asSentence Ecstacy%2Fmethamphetamine+trigger+concerted+proteolytic+attacks+on+Spna2+and+tau+proteins+by+calpain+and+caspase+family+of+proteases. assertion.
- assertion asSentence NSE+and+Tau+are+abundantly+expressed+in+the+brain+cells+and+MSC-derived+neurocyte-like+cells. assertion.
- assertion asSentence Activation+of+protein+kinase+C+induces+the+ubiquitylation+and+internalization+of+carboxy-terminal+lysine+residues+in+GLT1%2C+a+modification+that+mediates+interaction+of+GLT1+transporter+with+the+endocytic+machinery. assertion.
- assertion asSentence Glial-specific+glutamate+transporter+1+expression+is+significantly+reduced+following+spinal+cord+injury. assertion.
- assertion asSentence Subcellular+distribution+and+dynamic+remodeling+of+predominant+GLT-1+into+discrete+clusters+is+examined+in+developing+hippocampal+astrocytes. assertion.
- assertion asSentence PSD95+is+critical+for+promoting+synaptic+RAS-GTPase+activating+protein+%28SynGAP%29+serine+phosphorylation+after+transient+brain+ischemia. assertion.
- assertion asSentence Dexamethasone+exerts+a+time-dependent+and+redundant+inhibitory+effect+on+Egfr-mediated+proliferative+signaling+in+hepatocytes%2C+targeting+ErbB+proteins+and+their+positive%2Fnegative+effectors. assertion.