Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence Activation+of+Tie1+ectodomain+cleavage+increases+cartilage+oligomeric+protein+angiopoietin+1+activation+of+Tie2. assertion.
- assertion asSentence Angiopoietin-1+targeted+RNA+interference+suppresses+angiogenesis+and+tumor+growth+of+esophageal+cancer. assertion.
- assertion asSentence Angiogenesis+and+hepatic+fibrosis+are+mutually+stimulatory%2C+such+that+fibrosis+requires+angiogenesis+and+angiogenesis+requires+angiopoietin+1+from+activated+HSCs. assertion.
- assertion asSentence Serum+Ang-1+is+as+useful+a+marker+for+the+diagnosis+of+early+rheumatoid+arthritis+as+serum+anti-CCP+antibody. assertion.
- assertion asSentence Ang-2+is+expressed+in+areas+undergoing+vascular+remodeling+and+is+involved+in+neovascularization. assertion.
- assertion asSentence There+is+no+association+between+carrier+state+of+Ang2%28-35%29+and+risk+of+ROP+in+preterm+infants. assertion.
- assertion asSentence Elevated+circulating+serum+Ang-2+levels+are+associated+with+increased+hospital+mortality+in+patients+with+sepsis. assertion.
- assertion asSentence ANT3+overexpression+induces+apoptosis+in+cultured+cells. assertion.
- assertion asSentence Annexin+II+serves+as+both+ligand+and+receptor+in+promoting+phagocytosis. assertion.
- assertion asSentence Loss+of+Annexin-1+is+associated+with+invasive+breast+cancer. assertion.
- assertion asSentence IRF-1+silencing+with+siRNA+produced+upmodulation+of+the+Annexin-II+protein+in+THP-1+cells. assertion.
- assertion asSentence Annexin+A2+expression+is+required+for+the+biologic+effects+of+progastrin+in+vivo+and+in+vitro. assertion.
- assertion asSentence Aberrant+expression+of+Annexin+A2+and+Cdc42+play+a+role+in+carcinogenesis%2C+differentiation+and+metastasis+of+esophageal+squamous+cell+carcinomas. assertion.
- assertion asSentence Patients+with+sickle+cell+disease+have+elevated+plasma+levels+of+annexin+A5-+and+phosphatidylserine-exposing+microparticles. assertion.
- assertion asSentence AnxA6+interferes+with+caveolin+transport+through+the+inhibition+of+cPLA%282%29. assertion.
- assertion asSentence Partial+loss+of+function+of+APC+protein+by+truncation+of+its+carboxy%28C%29-terminus+is+an+early+factor+in+the+development+of+many+colorectal+neoplasms. assertion.
- assertion asSentence The+APC+mutations+associated+wiht+desmoid+tumors+and+responsible+for+the+behavior+of+the+invasiveness+of+these+neoplasms. assertion.
- assertion asSentence APC+mutations+are+important+in+development+of+the+cribiform-morula+variant+of+papillary+thyroid+carcinoma%28an+extracolonic+manifestations+of+familial+adenomatous+polyposis%29occurring+mostly+in+the+5%27+side+of+the+APC+gene+between+codons+308+and+935. assertion.
- assertion asSentence APC+mutations+are+associated+with+poor+response+to+5-fluorouracil+adjuvant+chemotherapy+in+Taiwanese+colorectal+cancer. assertion.
- assertion asSentence Mutations+in+APC+is+associated+with+stability+of+APC+gene+sequences+and+DNA+repair+and+leads+to+colorectal+carcinogenesis. assertion.
- assertion asSentence Cysteine+residue+%28Cis-65%29+of+the+APE1+protein+controls+APE1+subcellular+trafficking+and+plays+important+role+in+tumorigenesis. assertion.
- assertion asSentence Interferon-beta+therapy+exerts+a+regulatory+effect+on+peripheral+T+lymphocytes+through+an+anti-apoptosis+mechanism+that+involves+the+downregulation+of+cellular+Inhibitor+of+Apoptosis+Protein+expression. assertion.
- assertion asSentence Human+X-linked+variable+immunodeficiency+caused+by+a+hypomorphic+mutation+in+XIAP+in+association+with+a+rare+polymorphism+in+CD40LG. assertion.
- assertion asSentence This+nuclear+shuttling+protein+is+exported+actively+from+the+nucleus+via+the+CRM1-dependent+pathway. assertion.
- assertion asSentence High+expression+level+of+survivin+and+its+splice+variants+have+important+roles+in+the+progression+of+human+colorectal+carcinomas. assertion.
- assertion asSentence The+expression+of+Survivin+and+PTEN+proteins+are+closely+related+to+the+prognosis+of+adrenal+tumors. assertion.
- assertion asSentence Overexpression+of+survivin+in+endothelial+cells+serves+as+a+protective+mechanism+that+defends+the+vasculature+from+drug+cytotoxicity. assertion.
- assertion asSentence Insulin+induces+survivin+expression+via+the+PI3K+signalling+pathway. assertion.
- assertion asSentence RET+interacts+in+vivo+with+aryl+hydrocarbon+receptor-interacting+protein+to+alter+survivin+availability. assertion.
- assertion asSentence Nuclear+survivin+expression+is+a+strong%2C+independent+prognostic+marker+for+poor+clinical+outcomes+in+epithelial+ovarian+carcinoma. assertion.
- assertion asSentence An+important+role+of+survivin+-31+G%2FC+polymorphism+with+cancer+risk+especially+in+Asian+population. assertion.
- assertion asSentence Persistent+activation+of+signaling+by+the+AKT-survivin+pathway+induced+by+PTEN+loss+underlies+a+mechanism+of+resistance+to+erlotinib-induced+apoptosis+in+EGFR+mutation-positive+non-small+cell+lung+cancer. assertion.
- assertion asSentence Both+APLP1+and+APLP2%2C+form+transcriptionally+active+triple+protein+complexes+with+Mint3+and+transcriptional+co-activators+Taz+andYap. assertion.
- assertion asSentence Low+level+of+APO+A-I+is+associated+with+a+marked+impairment+of+effective+arterial+volume%2C+multiple+organ+dysfunction+and+a+poor+prognosis. assertion.
- assertion asSentence Nevirapine+increases+high-density+lipoprotein+cholesterol+concentration+by+stimulation+of+apolipoprotein+A-I+production. assertion.
- assertion asSentence The+MEK1%2F2-ERK1%2F2+MAP-kinase+cascade+and+nuclear+receptors+PPARalpha+and+LXRs+are+important+for+TNFalpha-mediated+apoA-I+promoter+switching. assertion.
- assertion asSentence Impact+of+self-association+on+function+of+apolipoprotein+A-I. assertion.
- assertion asSentence ApoB+and+ApoB%2FApoA-I+ratio+increased+in+adolescents+frequently+exposed+to+tobacco+smoke. assertion.
- assertion asSentence LDLR+986G%3EA%2C+1747C%3ET+and+APOB+10579C%3ET+are+common+mutations%2C+with+combined+frequency+of+approximately+33%25+in+familial+hypercholesterolemia+patients+in+Taiwan. assertion.
- assertion asSentence Polymorphism+is+associated+with+neurodegenerative+diseases%2C+notably+Alzheimer+disease. assertion.
- assertion asSentence In+young+adults%2C+the+APOE+epsilon4+allele+and+cigarette+smoking+act+synergistically%2C+increasing+an+individual%27s+propensity+to+have+a+cerebral+ischemic+event. assertion.
- assertion asSentence Polymorphisms+in+the+APOE+promoter+are+found+not+to+be+risk+factors+for+Alzheimer%27s+disease+nor+are+they+associated+with+parenchymal+or+vascular+accumulation+of+amyloid-beta+protein. assertion.
- assertion asSentence Epsilon+4+allele+is+more+often+associated+with+a+lack+of+response+to+current+antiepileptic+drugs+in+complex+partial+seizurese. assertion.
- assertion asSentence Coronary+artery+disease+is+associated+with+Alzheimer+disease+neuropathology+in+APOE4+carriers. assertion.
- assertion asSentence If+a+common+pathogenic+mechanism+exists+for+the+two+age-related+neurodegenerative+diseases%2C+primary+open-angle+glaucoma+and+alzheimer+disease%2C+it+does+not+involve+APOE+polymorphisms. assertion.
- assertion asSentence APOE+epsilon+4+allele+is+more+frequent+in+children+with+obstructive+sleep+apnea+and+particularly+in+those+who+develop+cognitive+dysfunction. assertion.
- assertion asSentence Men+with+APOE+Kyoto+mutation+are+at+increased+risk+for+lipoprotein+glomerulopathy. assertion.
- assertion asSentence APOE+plays+an+important+role+in+obesity+development+in+the+Roma+population. assertion.
- assertion asSentence TJ+integrity+in+BBB+is+regulated+by+apoE+in+an+isoform-dependent+manner. assertion.
- assertion asSentence One+of+20+episodes+of+acute+pancreatitis+is+caused+by+hypertriglyceridemia+and+it+is+linked+to+apoE+genetic+polymorphisms+and+comorbid+factors+such+as+diabetes+and%2C+especially%2C+alcohol+consumption. assertion.
- assertion asSentence The+soluble+amino-terminal+ectodomain+of+beta-amyloid+precursor+protein+regulates+dendrite+motility+and+melanin+release+in+epidermal+melanocytes+and+melanoma+cells. assertion.
- assertion asSentence In+cells+stably+overexpressing+the+functional+PAC1+receptors%2C+PACAP-27+%26+PACAP-38+strongly+stimulated+alpha-secretase+cleavage+of+APP. assertion.
- assertion asSentence Deleterious+post-translational+modifications+of+APP+accumulate+in+a+pathological+protein+fraction+in+Alzheimer+dissease. assertion.
- assertion asSentence Fe65+can+control+luciferase+activity+without+stabilizing+the+labile+APP+intracellular+domain+fragment. assertion.
- assertion asSentence Interaction+of+APP+with+toxic+Abeta-species+promotes+toxicity+in+hippocampal+neurons+by+a+mechanism+that+involves+APP-mediated+Go+protein+activation%2C+revealing+an+Abeta-receptor-like+function+of+APP+directly+implicated+in+neuronal+degeneration+in+AD. assertion.
- assertion asSentence Intracellular+copper+deficiency+increases+amyloid-beta+secretion+by+diverse+mechanisms. assertion.
- assertion asSentence Tau+phosphorylation+at+Ser262+is+crucial+for+Abeta42-induced+tau+toxicity+in+vivo. assertion.
- assertion asSentence MMP-2+release+and+activation+differentially+degrades+Abeta+species%2C+delaying+their+toxicity+for+endothelial+cells. assertion.
- assertion asSentence APP%2C+specifically+tyrosine+residue+682%2C+regulates+activation+of+the+nerve+growth+factor+NGF%2FTrkA+receptor+signaling+pathway+in+vivo%2C+the+subcellular+distribution+of+TrkA+and+the+sensitivity+of+neurons+to+the+trophic+action+of+NGF. assertion.
- assertion asSentence ERalpha+and+metabotropic+%28mGlu1%29+receptors+interact+in+neurons+to+produce+neuroprotection+against+beta-amyloid+toxicity. assertion.
- assertion asSentence MOCA+is+a+key+molecule+of+the+Alzheimer+disease-relevant+neuronal+death+signals+that+links+the+presenilin-mediated+death+signal+with+the+APP-mediated+death+signal+at+a+point+between+Rac1+or+Cdc42+and+ASK1. assertion.
- assertion asSentence The+homocysteinylation+of+lysine+residues+increase+the+neurotoxicity+of+the+Abeta+peptide+by+stabilizing+soluble+oligomeric+intermediates. assertion.
- assertion asSentence Abeta-induced+release+of+gliotransmitter+ATP+plays+a+protective+role+against+Abeta%281-42%29-mediated+disruption+of+synaptic+plasticity. assertion.
- assertion asSentence Calcitriol+inhibits+growth+and+induces+AR+and+PSA+expression+in+a+prostate+tumor+cell+line. assertion.
- assertion asSentence Androgen+response+element+of+polymorphism+on+PSA+gene+is+associated+with+prostate+cancer. assertion.
- assertion asSentence Fas-mediated+apoptosis+play+an+important+role+in+pathogenesis+of+chronic+hepatitis+B. assertion.
- assertion asSentence Fas-670+polymorphism+is+not+associated+with+inflammatory+bowel+disease+in+Chinese+patients. assertion.
- assertion asSentence FAS+polymorphisms+contribute+to+susceptibility+of+lung+cancer. assertion.
- assertion asSentence TNF-alpha+sensitizes+primarily+resistant+endometrial+stromal+cells+to+Fas-mediated+apoptosis. assertion.
- assertion asSentence High+serum+Fas+is+associated+with+cancer. assertion.
- assertion asSentence Up-regulation+of+FasL+expression+plays+an+important+role+in+invasive+depth%2C+histological+classification+and+metastasis+of+gallbladder+carcinoma. assertion.
- assertion asSentence FAS-1377%2C+FAS-670+and+FASL-844+polymorphisms+are+not+susceptible+factors+of+silicosis. assertion.
- assertion asSentence Individually+expressed+HSV-1+R1+%28ICP6%29+shares%2C+with+HSV-2+R1%2C+the+ability+to+bind+caspase-8+and+to+protect+cells+against+death+receptor-induced+apoptosis. assertion.
- assertion asSentence Fas+and+FasL+mediated+alveolar+macrophage+apoptosis+in+human+silicosis. assertion.
- assertion asSentence AMPK+regulates+expression+of+FASL+and+COX-2+via+the+protein+kinase+C+theta+-+dependent+pathway+in+activated+Jurkat+cells. assertion.
- assertion asSentence AQP1+mRNA+and+protein+expression+level+in+laryngeal+tumor+tissues+is+remarkably+stronger+than+that+in+normal+tissues. assertion.
- assertion asSentence AQP1+activity+of+cell+membrane+affects+HT20+colon+cancer+cell+migration. assertion.
- assertion asSentence Exaggerated+urinary+excretion+of+AQP-2+is+dependent+on+baroreceptor-mediated+release+of+arginine+vasopressin+in+patients+with+congestive+heart+failure. assertion.
- assertion asSentence The+distribution+and+expression+levels+of+AQP3+in+normal+human+tissue. assertion.
- assertion asSentence AQP3+water+channels+serve+as+an+essential+pathway+for+volume-regulatory+water+transport+in+human+epithelial+cells. assertion.
- assertion asSentence AQP4+is+not+expressed+in+human+airway+epithelial+cells+from+the+A549+adeoncarcinoma+cell+line. assertion.
- assertion asSentence A+specific+role+for+AQP4+in+square+array+formation+and+water+permeability. assertion.
- assertion asSentence HLA-DRB1+alleles+influence+susceptibility+to+anti-aquaporin+4+antibody+positive+multiple+sclerosis+in+Japanese+patients. assertion.
- assertion asSentence Almost+all+of+the+amino+acids+located+at+the+13-residue+C-terminal+end+of+the+androgen+receptor+participate+in+its+ligand+binding+function+and+consequently+in+its+transcriptional+activation. assertion.
- assertion asSentence Pim1+and+Etk+are+required+for+IL6-induced+activation+of+androgen+receptor-mediated+transcription+in+prostate+cancer. assertion.
- assertion asSentence Among+postmenopausal+Caucasian+women%2C+common+variants+of+the+AR+gene+are+not+associated+with+risk+of+breast+cancer. assertion.
- assertion asSentence ZIP+kinase+plays+a+crucial+role+in+androgen+receptor-mediated+transcription. assertion.
- assertion asSentence The+nuclear+import+of+AR+is+regulated+by+the+interplay+between+each+domain+of+the+AR. assertion.
- assertion asSentence The+androgen+receptor+fuels+prostate+cancer+by+regulating+central+metabolism+and+biosynthesis. assertion.
- assertion asSentence YB-1+induces+castration+resistance+in+androgen-dependent+prostate+cancer+cells+via+AR+expression. assertion.
- assertion asSentence AR+is+enriched+in+ER-+breast+tumors+that+overexpress+HER2. assertion.
- assertion asSentence A-Raf+interacts+with+MEK1+and+activates+MEK1+by+phosphorylation. assertion.
- assertion asSentence hnRNP+H+blocks+MST2-mediated+apoptosis+in+cancer+cells+by+regulating+A-Raf+transcription. assertion.
- assertion asSentence A+phosphatidylinositol-3-kinase-dependent+signal+transition+defines+the+sequence+of+ARF1+activation+during+phagocytosis. assertion.
- assertion asSentence Arf6+plays+a+crucial+role+in+the+generation+of+a+phosphatidylinositol4%2C5-bisphosphate+%28PIP2%29+plasma+membrane+pool+required+for+cytolytic+granule-mediated+target+cell+killing. assertion.
- assertion asSentence A+phosphatidylinositol-3-kinase-dependent+signal+transition+defines+the+sequence+of+ARF6+activation+during+phagocytosis. assertion.
- assertion asSentence Fbx8%2C+an+F-box+protein+bearing+the+Sec7+domain%2C+mediates+ubiquitination+of+Arf6. assertion.
- assertion asSentence ARF6+activated+by+the+LHCG+receptor+through+the+cytohesin+family+of+guanine+nucleotide+exchange+factors+mediates+the+receptor+internalization+and+signaling. assertion.
- assertion asSentence Increased+ARG1+plasma+levels+are+associated+with+nonsmall+cell+lung+cancer. assertion.
- assertion asSentence Human+arginase+I+is+a+binuclear+manganese+metalloenzyme+that+catalyzes+the+hydrolysis+of+L-arginine+to+generate+L-ornithine+and+urea. assertion.