Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence The+functional+CB%282%29+cannabinoid+receptor+is+present+in+human+spermatozoa+and+regulates+the+sperm+motility+in+a+more+distinct+manner+than+CB%281%29. assertion.
- assertion asSentence Squamous+cell+carcinoma+over-expresses+CB2+at+both+the+protein+and+mRNA+levels. assertion.
- assertion asSentence A+four+base-pair+insertion+polymorphism+of+the+COL1A1+gene+is+not+associated+with+the+presence+of+lumbar+disk+disease+in+young+Greek+males. assertion.
- assertion asSentence Genotype+COL1A1+is+associated+with+arterial+fluid+markers+in+patients+with+COPD+and+bronchial+asthma. assertion.
- assertion asSentence Cells+with+TT+genotype+have+low+expression+of+mRNA+of+COL+I+A1+gene+and+less+collagen+type+I+and+calcium+in+cell+matrix+and+calcium+nodus+of+osteoblasts. assertion.
- assertion asSentence The+COL1A2+endodeoxyribonuclease+PvuII+binding+site+polymorphism+is+associated+with+nonosteoporotic+fractures+in+prepubertal+girls+independently+of+bone+density. assertion.
- assertion asSentence Chondroitin+sulphate+and+its+derived+hydrolytic+fragments+%28CSf%29+repress+COL1A1+gene+transcription+through+a+-112%2F-61+bp+sequence+upstream+the+start+site+of+transcription+and+imply+hc-Krox+and+Sp1+transcription+factors. assertion.
- assertion asSentence Hypoxia-inducible+factor+1alpha+inhibits+the+fibroblast-like+markers+type+I+and+type+III+collagen+during+hypoxia-induced+chondrocyte+redifferentiation. assertion.
- assertion asSentence SOX9+exerts+a+bifunctional+effect+on+COL2A1+gene+expression+in+chondrocytes+depending+on+the+differentiation+state. assertion.
- assertion asSentence There+is+no+correlation+between+the+severity+of+the+glomerular+involvement+%28expressed+by+proteinuria%29+and+the+staining+of+the+alpha+5+chain+in+the+EBM+in+females+with+X-linked+Alport+syndrome. assertion.
- assertion asSentence Comparison+of+alpha5%28IV%29+with+alpha2%28IV%29+expression+in+Alport+patients+is+simple+and+eliminates+technical+artifacts. assertion.
- assertion asSentence Finds+the+COL5A1+BstUI+RFLP+associated+with+Achilles+tendon+pathology+and+more+specifically%2C+chronic+ATP. assertion.
- assertion asSentence The+crystal+structure+at+2.0+A+resolution+of+the+human+collagen+X+NC1+domain+reveals+an+intimate+trimeric+assembly+strengthened+by+a+buried+cluster+of+calcium+ions. assertion.
- assertion asSentence Collagen+XVI+promotes+persistence+of+intestinal+subepithelial+myofibroblasts+in+the+normal+and+in+the+inflamed+bowel+wall+by+stabilizing+focal+adhesion+contacts. assertion.
- assertion asSentence 14-3-3sigma+isoform+interacts+with+BP180+in+keratinocytes. assertion.
- assertion asSentence Collagen+XVII+%28BP180%29+modulates+keratinocyte+expression+of+the+proinflammatory+chemokine%2C+IL-8. assertion.
- assertion asSentence The+COMT+Val108%2F158Met+polymorphism+%28rs4680%29+significantly+interacted+with+maternal+cigarette+smoking+during+pregnancy+to+predict+youth+aggressive+behavior+at+ages+15+and+20. assertion.
- assertion asSentence %5Breview%5D+COMT+is+involved+in+the+metabolism+of+dopamine%2C+a+key+neurotransmitter+found+to+be+associated+with+schizophrenia+pathophysiology. assertion.
- assertion asSentence COMT+activity+do+not+play+a+significant+role+in+pain+perception+and+TEAS-induced+analgesia+in+the+Chinese+Han+male+population. assertion.
- assertion asSentence Under+conditions+of+reduced+oxygen+availability%2C+hypoxia-inducible+factor+1+reciprocally+regulates+COX4+subunit+expression+by+activating+transcription+of+the+genes+encoding+COX4-2+and+LON%2C+a+mitochondrial+protease+that+is+required+for+COX4-1+degradation. assertion.
- assertion asSentence ROS+affects+RNA-protein+complex+formation+to+promote+Cp+mRNA+decay. assertion.
- assertion asSentence The+roles+of+selected+arginine+and+lysine+residues+of+TAFI+%28Pro-CPU%29+in+its+activation+to+TAFIa+by+the+thrombin-thrombomodulin+complex. assertion.
- assertion asSentence Reduced+claudin-4+expression+correlates+with+loss+of+differentiation+in+thyroid+neoplasms. assertion.
- assertion asSentence All+other+type+of+mutations+or+missense+mutations+mapped+elsewhere+throughout+the+CPO+gene%2C+lead+to+coproporphyrin+accumulation+and+subsequently+typical+HCP. assertion.
- assertion asSentence Coligation+of+CD21+with+the+B+cell+antigen+receptor+lowers+the+antigen+concentration+threshold+for+eliciting+protection+from+Fas+apoptosis+by+2-3+orders+of+magnitude. assertion.
- assertion asSentence Aberrant+methylation+in+CRABP-II+reduces+the+expression+of+CRABP-II+that+in+turn+confers+retinoic+acid+resistance+in+medulloblastoma+cells. assertion.
- assertion asSentence Overexpression+of+phosphorylated-ATF2+and+STAT3+in+cutaneous+squamous+cell+carcinoma%2C+Bowen%27s+disease+and+basal+cell+carcinoma. assertion.
- assertion asSentence CREB+binding+proten+affects+Proteinase-activated+receptor-2+and+cyclooxygenase+2+expression. assertion.
- assertion asSentence The+acetylase%2Fdeacetylase+couple+CREB-binding+protein%2FSirtuin+1+controls+hypoxia-inducible+factor+2+signaling. assertion.
- assertion asSentence Common+variants+of+the+CREM+gene+are+involved+in+the+genetic+component+conferring+general+susceptibility+to+inflammatory+bowel+disease+in+the+Tunisian+population. assertion.
- assertion asSentence CRH+modulates+human+cardiovascular+and+pupillary+autonomic+reflexes. assertion.
- assertion asSentence CRH+promoter+reactivity+varies+between+the+compound+promoter+alleles. assertion.
- assertion asSentence MicroRNA-34c+transgene+reduces+the+responsiveness+of+cells+to+stress-related+corticotropin+releasing+factor+CRF+in+neuronal+cells+endogenously+expressing+CRFR1. assertion.
- assertion asSentence CRHR2+polymorphisms+examined+do+not+confer+susceptibility+to+panic+disorder. assertion.
- assertion asSentence Both+CRHR1+and+CRHR2+play+a+facilitatory+role+in+the+non-clathrin-%2C+non-caveolae-mediated+endocytosis+and+intracellular+signal+transduction+of+urocortin. assertion.
- assertion asSentence Structural+basis+for+hormone+recognition+by+the+Human+CRFR2%7Balpha%7D+G+protein-coupled+receptor. assertion.
- assertion asSentence Physical+fitness+is+inversely+related+to+CRP+level+in+children%2C+a+relationship+that+is+more+pronounced+in+boys+than+in+girls. assertion.
- assertion asSentence CRP+directs+uptake+of+Streptococcus+pneumoniae+to+Fc+gamma+receptors+on+dendritic+cells%2C+enhancing+effective+uptake+and+presentation+of+bacterial+antigens+and+stimulating+protective+adaptive+immunity. assertion.
- assertion asSentence No+relationship+between+serum+CRP+levels+and+the+presence+and+severity+of+coronary+artery+disease+in+patients+with+stable+angina. assertion.
- assertion asSentence Levels+of+high+sensitivity+C-reactive+protein+and+tumor+necrosis+factor-alpha+have+a+cumulative+effect+on+the+mean+values+of+carotid+artery+intimal+medial+thickness+in+Asian+Indian+subjects+with+normal+glucose+tolerance. assertion.
- assertion asSentence Increased+C+reactive+protein+%28CRP%29+levels+in+systemic+scleroderma+correlated+with+P+selectin+and+Platelet+Glycoprotein+GPIIbIIIa+complex+expression. assertion.
- assertion asSentence CRP+%2B1444+C--%3ET+and+TNF-alpha+-308+G--%3EA+polymorphisms+are+associated+with+predisposition+to+Kawasaki+disease+and%2C+in+patients+with+Kawasaki+disease%2C+increased+carotid+arterial+stiffness+and+intima-media+thickness+in+the+long-term. assertion.
- assertion asSentence The+level+of+serum+IL-6+or+genetic+IL-6+polymorphism+is+correlated+with+the+complexity+of+coronary+plaque+in+patients+with+stable+coronary+artery+disease+%28CAD%29. assertion.
- assertion asSentence Serum+leptin+is+an+independent+factor+associated+with+C-reactive+protein+in+Korean+type+2+diabetic+patients. assertion.
- assertion asSentence Coronary+arterial+remodeling%2C+fibrous+cap+thickness+and+hs-CRP+level+in+patients+with+acute+coronary+syndrome+are+associated+with+each+other. assertion.
- assertion asSentence Increased+preprocedural+serum+CRP+levels+would+predict+higher+major+adverse+cardiac+events+and+restenosis+rates+after+sirolimus-eluting+stents+implantation+in+patients+on+hemodialysis. assertion.
- assertion asSentence Simvastatin+and+ezetimibe+lowered+C-reactive+protein+in+patients+with+hypercholesterolemia. assertion.
- assertion asSentence Visceral+fat+thickness+is+the+strongest+contributor+to+the+systemic+CRP+concentrations+in+patients+with+vascular+diseases. assertion.
- assertion asSentence High+C-Reactive+Protein+is+associated+with+increased+mortality. assertion.
- assertion asSentence C-reactive+protein+levels+predict+the+risk+of+myocardial+infarction+among+white+men. assertion.
- assertion asSentence CRP+has+no+prognostic+value+in+melanoma+patients+treated+with+adjuvant+interferon-alpha. assertion.
- assertion asSentence Exposing+a+hidden+functional+site+of+C-reactive+protein+by+site-directed+mutagenesis. assertion.
- assertion asSentence Soluble+CD40+ligand%2C+high+sensitive+C-reactive+protein+and+fetuin-A+levels+in+patients+with+essential+thrombocythemia. assertion.
- assertion asSentence Proper+orientation+of+residues+contributing+to+RS-1+and+RS-2+sites+in+alphaB-crystallin+is+important+for+homooligomerization+and+optimal+subunit+interaction+with+alphaA-crystallin. assertion.
- assertion asSentence Unlike+wild+type+alphaA-crystallin%2C+G98R+AlphaA-crystallin+and+its+mixed+oligomers+with+wild+type+protein+are+vulnerable+to+heavy+metal+ions. assertion.
- assertion asSentence A+G--%3ET+splice+site+mutation+of+CRYBA1%2FA3+associated+with+autosomal+dominant+suture+cataracts+in+a+Chinese+family. assertion.
- assertion asSentence Hydrophobic+cluster+residues+of+gammaD+crystallin+contribute+to+protein+folding+and+protein+stability. assertion.
- assertion asSentence Zeta-Crystallin+is+a+bcl-2+mRNA+binding+protein+involved+in+bcl-2+overexpression+in+T-cell+acute+lymphocytic+leukemia. assertion.
- assertion asSentence The+expression+of+tenascin-W+is+dependent+on+p38MAPK+and+JNK+signaling+pathways+in+mammary+tumors. assertion.
- assertion asSentence Sin1+binds+directly+to+both+ATF-2+and+p38. assertion.
- assertion asSentence IL-17+is+a+potent+inducer+of+CRP+expression+via+p38+MAPK+and+ERK1%2F2-dependent+NF-kappaB+and+C%2FEBPbeta+activation. assertion.
- assertion asSentence Whether+MAP+kinase+phosphatase+%28MKP%29-1%2C+a+negative+regulator+of+p38+and+JNK%2C+mediates+the+antiinflammatory+effects+of+shear+stress. assertion.
- assertion asSentence A+critical+role+for+the+Pyk2+mediated+pathway+involving+p38+MAP+kinase+and+NF-kappaB+in+LPS-induced+MCP-1+production+in+human+microvascular+endothelial+cells. assertion.
- assertion asSentence The+activation+of+EGR-1+mediated+by+p38MAPK+pathway+plays+a+critical+role+in+epirubicin+resistance+of+human+breast+carcinoma+cells. assertion.
- assertion asSentence Demonstrate+antinociceptive+effects+in+acute+pain+with+preoperative+administration+of+a+p38alpha+MAPK+inhibitor. assertion.
- assertion asSentence Macrophage+colony-stimulating+factor+and+receptor+activator+NF-kappaB+ligand+fail+to+rescue+osteoclast-poor+human+malignant+infantile+osteopetrosis+in+vitro. assertion.
- assertion asSentence GM-CSF+induces+the+protein+expression+of+cyclin+D3+and+the+kinase+Pim-1%2C+both+of+which+are+regulated+by+STAT-dependent+processes+in+airway+and+blood+eosinophils. assertion.
- assertion asSentence GM-CSF+derived+from+cultured+skeletal+muscle+cells+after+mechanical+strain+promote+neutrophil+chemotaxis+in+vitro. assertion.
- assertion asSentence Two+different+modes+of+beta+c+binding+are+utilized+in+the+presence+of+the+hIL-3R+alpha+isoforms. assertion.
- assertion asSentence Induces+autocrine+production+of+epithelial+cell-derived+neutrophil+attractant-78+in+neutrophils. assertion.
- assertion asSentence PTPIP51+is+phosphorylated+by+Lyn+and+c-Src+kinases+lacking+dephosphorylation+by+PTP1B+in+acute+myeloid+leukemia. assertion.
- assertion asSentence mTOR+cooperates+with+CK1alpha+and+betaTrCP+to+generate+an+auto-amplification+loop+to+promote+its+own+full+activation. assertion.
- assertion asSentence Ligand-dependent+ubiquitination+of+Smad3+is+regulated+by+CK1g2%2C+an+inhibitor+of+TGF-beta+signaling. assertion.
- assertion asSentence Consequences+of+CK2+signaling+to+the+nuclear+matrix. assertion.
- assertion asSentence CK2+is+the+kinase+responsible+for+phosphorylating+Pax3+and+oncogenic+fusion+protein+Pax3-FOXO1+at+serine205+in+proliferating+mouse+primary+myoblasts+and+in+a+variety+of+translocation-containing+alveolar+rhabdomyosarcoma+cell+lines. assertion.
- assertion asSentence CK-II-dependent+PPARgamma+phosphorylation+at+Ser16+and+Ser21+is+necessary+for+CRM1%2FRan%2FRanBP3-mediated+nucleocytoplasmic+translocation+of+PPARgamma. assertion.
- assertion asSentence The+primary+mechanisms+by+which+apigenin+kill+multiple+myeloma+cells+is+by+targeting+the+trinity+of+CK2-Cdc37-Hsp90. assertion.
- assertion asSentence Response+of+cancer+cells+to+molecular+interruption+of+the+CK2+signal. assertion.
- assertion asSentence CK2+activity+in+Chinese+Hamster+Ovary+%28CHO%29+cells+is+entirely+accounted+for+by+the+holoenzyme. assertion.
- assertion asSentence Serum+cystatin+C+level+on+admission+in+patients+with+heart+failure+with+preserved+ejection+fraction+is+a+strong+and+independent+predictor+of+unfavorable+outcome. assertion.
- assertion asSentence Cystatin+D+is+a+candidate+tumor+suppressor+gene+induced+by+vitamin+D+in+human+colon+cancer+cells. assertion.
- assertion asSentence CTGF+promotes+melanoma+cell+invasion+and+migration+and%2C+therefore%2C+has+an+important+role+in+the+progression+of+malignant+melanoma. assertion.
- assertion asSentence Surface+cytotoxic+T+lymphocyte-associated+antigen+4+partitions+within+lipid+rafts+and+relocates+to+the+immunological+synapse+under+conditions+of+inhibition+of+T+cell+activation. assertion.
- assertion asSentence -318+C%2FT+variant+in+the+promoter+region+of+the+CTLA-4+gene+is+associated+with+human+papillomavirus-16-associated+cervical+squamous+cell+carcinoma+in+Taiwanese+women. assertion.
- assertion asSentence The+proximal+promoter+of+CTLA-4+contains+an+NFAT+consensus+sequence+critical+for+activating+the+CTLA-4+gene+in+human+lymphocytes. assertion.
- assertion asSentence Common+allelic+variants+in+promoter+regions+of+genes+encoding+for+molecules+involved+in+either+the+innate+%28CD14%29+or+adoptive+%28CTLA-4%29+immune+reactions+are+associated+with+an+increased+risk+of+GVHD+after+allogeneic+stem+cell+transplantation. assertion.
- assertion asSentence CTLA4+AND+PDCD1+are+genes+encoding+coinhibitory+immunoreceptors+that+harbor+polymorphisms+with+demonstrated+associations+to+multiple+autoimmune+disorders. assertion.
- assertion asSentence Combination+of+CTLA-4+and+TGFbeta1+polymorphisms+is+associated+with+the+susceptibility+of+DHF+and+higher+virus+load. assertion.
- assertion asSentence A%2FG+polymorphism+of+CTLA+molecule+is+linked+to+occurrence+of+Graves%27+disease+bu+not+to+HT+in+the+Turkish+population. assertion.
- assertion asSentence SNP+CT60+in+the+CTLA4+gene+plays+only+a+minor+role+in+genetic+susceptibility+to+childhood+asthma+in+the+Caucasian+population. assertion.
- assertion asSentence CTLA4+gene+-1661A%2FG+and+long+3%27+untranslated+region+%28AT%29n+repeat+polymorphisms+are+associated+with+UC+in+Central+China. assertion.
- assertion asSentence Over+expression+of+TGF-beta+and+CTLA-4+leads+to+T+cell+hyporesponsiveness%2C+a+major+hallmark+of+leprosy%2C+by+increasing+the+expression+of+Cbl-b. assertion.
- assertion asSentence DCs+transfected+with+mRNA+encoding+a+humanized+anti-CTLA-4+mAb+and+mRNA+encoding+a+soluble+human+GITR-L+fusion+protein+enhance+the+induction+of+anti-tumor+CTLs+in+response+to+DCs. assertion.
- assertion asSentence Genetic+variation+in+CTLA4+gene+is+associated+with+acute+rejection+of+liver+transplantation. assertion.
- assertion asSentence The+MUC1%2Fbeta-catenin+interaction+occurs+in+primary+tumors%2C+%26+is+dramatically+increased+in+metastatic+lesions. assertion.
- assertion asSentence Splice+forms+of+crucial+genes+of+the+Wnt-pathway%2C+beta-Catenin%2C+LRP5%2C+GSK3beta%2C+Axin-1+and+CtBP1+are+expressed+in+human+colorectal+tissue. assertion.
- assertion asSentence Activating+mutations+of+exon+3+of+the+beta-catenin+gene+are+frequent+in+adrenocortical+adenomas. assertion.
- assertion asSentence Peroxisome+proliferator-activated+receptor+gamma+suppresses+colonic+epithelial+cell+turnover+and+colon+carcinogenesis+through+inhibition+of+the+beta-catenin%2FT+cell+factor+pathway. assertion.
- assertion asSentence Nuclear+beta-catenin+expression+provides+additional+information+in+predicting+patient+outcome+in+advanced+colorectal+cancer. assertion.
- assertion asSentence There+are+somatic+mutations+of+the+APC+and+beta-catenin+genes+in+aggressive+fibromatosis. assertion.