Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence The+occurrence+as+an+additional+hit+of+a+CTNNB1+somatic+mutation+is+associated+with+larger+or+more+aggressive+adrenocortical+tumors. assertion.
- assertion asSentence PTEN%2FAkt%2Fbeta-catenin+signaling+pathway+has+an+important+role+in+regulation+of+normal+and+malignant+mammary+stem%2Fprogenitor+cell+populations. assertion.
- assertion asSentence Mutations+of+beta-catenin+and+phosphorylation+is+associated+with+colon+cancer. assertion.
- assertion asSentence Growth+inhibition+of+magnolol+against+human+colon+cancer+cells+can+be+partly+attributed+to+the+regulation+of+the+Wnt%2Fbeta-catenin+signaling+pathway. assertion.
- assertion asSentence Plasma+cathepsin+D+isoforms+and+their+active+metabolites+increase+after+myocardial+infarction+and+contribute+to+plasma+renin+activity. assertion.
- assertion asSentence Myocardial+STAT3+protein+levels+are+reduced+and+serum+levels+of+activated+cathepsin+D+and+16+kDa+prolactin+are+elevated+in+postpartum+cardiomyopathy+patients. assertion.
- assertion asSentence Cathepsin+L+cleavage+potentiates+the+Ebola+virus+GP+to+undergo+a+fusion-relevant+conformational+change. assertion.
- assertion asSentence Cathepsins+L+and+Z+are+critical+in+degrading+polyglutamine-containing+proteins+within+lysosomes. assertion.
- assertion asSentence V249I+polymorphism+is+not+associated+wiwth+hepatocellular+carcinoma. assertion.
- assertion asSentence Genistein+combined+wwith+a+histone+deacetylase+inhibitor+can+inhibit+cancer+by+altering+the+transcriptional+regulation+of+CXADR. assertion.
- assertion asSentence Loss+of+the+coxsackie+and+adenovirus+receptor+contributes+to+gastric+cancer+progression. assertion.
- assertion asSentence Colocalization+of+CytB5+and+P450c17+strongly+supports+the+view+that+CytB5+plays+an+important+role+in+the+regulation+of+the+androgen+biosynthetic+pathway+in+the+fetal+and+adult+human. assertion.
- assertion asSentence CYB561+is+a+senescene-associated+gene+in+normal+human+oral+keratinocytes. assertion.
- assertion asSentence mRNA+expression+and+localization+of+NOX2+in+human+umbilical+vein+endothelial+cells. assertion.
- assertion asSentence There+are+no+associations+between+the+genotypes+and+the+risk+of+developing+acute+leukemia. assertion.
- assertion asSentence CYP1A1+Val%2FVal+and+GSTM1+deletion+genotypes+are+genetic+susceptibility+biomarkers+for+esophageal+cancer. assertion.
- assertion asSentence CYP1A1+is+a+suscpetibility+gene+for+lung+cancer+among+non-smoking+Asian+women+and+this+asscociation+can+be+influenced+by+environmental+tobacco+smoke+exposure. assertion.
- assertion asSentence Aryl+hydrocarbon+receptor+mediates+laminar+fluid+shear+stress-induced+CYP1A1+activation+and+cell+cycle+arrest+in+vascular+endothelial+cells. assertion.
- assertion asSentence Genetic+polymorphisms+of+metabolic+enzymes+CYP1A1%2C+CYP2D6%2C+GSTM1+and+GSTT1+and+leukemia+susceptibility. assertion.
- assertion asSentence Polymorphism+in+cytochrome+P4501A1+is+significantly+associated+with+head+and+neck+cancer+risk. assertion.
- assertion asSentence The+combined+effects+of+CYP1A1+gene+and+GSTM1+gene+polymorphism+are+significantly+associated+with+an+increased+risk+to+lung+cancer. assertion.
- assertion asSentence CYP240+peptide+from+CYP1B1+protein+is+spontaneously+recognized+by+HLA-A1+and+HLA-B35+restricted+CD8+T+cells+in+cancer+patients. assertion.
- assertion asSentence Genetic+variation+in+CYP1B1+has+at+most+a+minor+influence+on+breast+cancer+susceptibility. assertion.
- assertion asSentence Single-nucleotide+polymorphisms%2C+V432L+of+the+CYP1B1+gene+is+found+to+be+significantly+associated+with+the+risk+of+asthma. assertion.
- assertion asSentence Both+severe+congenital+corneal+opacification+and+isolated+infantile+glaucoma+are+associated+with+CYP1B1+mutations. assertion.
- assertion asSentence Downregulation+of+CYP1B1+is+associated+with+oral+squamous+cell+carcinoma. assertion.
- assertion asSentence Correlation+of+CYP2C19+genetic+polymorphisms+with+helicobacter+pylori+eradication+in+patients+with+cirrhosis+and+peptic+ulcer. assertion.
- assertion asSentence Adjunctive+cilostazol+significantly+enhances+platelet+inhibition+and+reduces+the+rate+of+high+on-treatment+platelet+reactivity%2C+especially+in+acute+myocardial+infarction+patients+with+CYP2C19+loss-of-function+variants. assertion.
- assertion asSentence CYP2C19%2A3+polymorphism+is+significantly+associated+with+laryngeal+carcinoma+in+the+Chinese+Han+population. assertion.
- assertion asSentence Cytochrome+b5+can+alter+multiple+steps+in+the+catalytic+cycle+via+complex+interactions+with+CYP2C9+and+P450+reductase. assertion.
- assertion asSentence Cytochrome+P-450+2C9+signaling+does+not+contribute+to+age-associated+vascular+endothelial+dysfunction+in+humans. assertion.
- assertion asSentence Polymorphisms+in+CYP2C9+is+not+associated+with+dosing+of+vitamin+K+antagonists+in+thrombosis. assertion.
- assertion asSentence VKORC1+and+CYP2C9+polymorphism+contribute+to+the+difference+dose+requirement+amongst+the+patients+. assertion.
- assertion asSentence CYP2D6%2C...expressed+at+rather+low+levels+compared+to...+other+human+CYPs%2C+plays+an+important+role+in+metabolism%2C+partially+or+to+a+major+extent+for+the+oxidative+biotransformation+of+a+variety+of+psychoactive+and+cardiovascular+drugs. assertion.
- assertion asSentence The+frequencies+of+functional+variant+alleles+of+CYP2D6+in+the+Czech+population+are+in+concordance+with+other+Caucasian+populations. assertion.
- assertion asSentence CYP2D6+genotype+significantly+affects+the+steady-state+serum+concentrations+of+risperidone+and+9-hydroxyrisperidone+in+patients+using+injectable+long-acting+risperidone. assertion.
- assertion asSentence Protein+concentration+of+CYP2E1+is+significantly+lower+by+~81%25+in+the+sigmoid+colon+compared+to+the+level+in+the+descending+colon. assertion.
- assertion asSentence Combined+associations+of+XRCC1+399Gln%2C+CYP2E1%2A5B+and+%2A6+alleles+with+the+risk+of+development+of+childhood+acute+lymphoblastic+leukemia. assertion.
- assertion asSentence CYP2E1+gene+polymorphisms+not+are+related+with+susceptibility+to+AML. assertion.
- assertion asSentence The+constructs%2C+CYP2C9%2FBMR%2C+CYP2C19%2FBMR+and+CYP3A4%2FBMR+are+well+expressed+in+Escherichia+coli+as+holo+proteins. assertion.
- assertion asSentence Single+nucleotide+polymorphism+in+CYP3A4+gene+is+associated+with+ovarian+cancer. assertion.
- assertion asSentence No+mutation+related+to+CYP3A4%2A17+and+CYP3A4%2A18+single+nucleotide+polymorphisms. assertion.
- assertion asSentence The+3%27-end+processing+of+CYP3A4+contributes+to+quantitative+regulation+of+CYP3A4+gene+expression+through+alternative+polyadenylation. assertion.
- assertion asSentence Low+CYP3A5+expression+is+associateed+with+cncreased+risk+of+vincristine+neurotoxicity+in+children+with+acute+lymphoblastic+leukemia. assertion.
- assertion asSentence Small+molecule+inhibition+of+the+APEX1+repressor+or+treatment+with+small+interfering+RNA+%28siRNA%29+leads+to+increased+CYP11B2+transcription. assertion.
- assertion asSentence Role+of+aromatase+in+endometrial+disease. assertion.
- assertion asSentence Spatially+heterogeneous+expression+of+aromatase+P450+through+promoter+II+is+closely+correlated+with+the+level+of+steroidogenic+factor-1+transcript+in+endometrioma+tissues. assertion.
- assertion asSentence Genetic+polymorphism+of+CYP19+are+associated+with+familial+prostate+carcinoma+risk. assertion.
- assertion asSentence Use+of+an+aromatase+inhibitor+for+ovulation+induction+does+not+eliminate+the+risk+for+higher+order+multiple+pregnancy. assertion.
- assertion asSentence A+CYP19+%28aromatase%29+polymorphism+is+associated+with+increased+premenopausal+breast+cancer+risk. assertion.
- assertion asSentence The+tumoral+tissues+exhibited+positive+staining+for+anti-aromatase+antibody. assertion.
- assertion asSentence Dab2+mediates+AP-2+independent+recruitment+of+CFTR+to+CCVs+in+polarized+human+airway+epithelial+cells. assertion.
- assertion asSentence DACH1+plays+an+important+role+in+negative+regulation+of+RANKL+gene+expression+in+marrow+stromal%2Fpreosteoblast+cells+in+the+bone+microenvironment. assertion.
- assertion asSentence Antiadhesive+role+of+apical+decay-accelerating+factor+%28CD55%29+in+human+neutrophil+transmigration+across+mucosal+epithelia. assertion.
- assertion asSentence UEA-1+agglutinin+binds+to+DAF+in+colonic+mucosa+and+the+product+is+excreted+in+feces+of+patients+with+colon+cancer+and+colitis. assertion.
- assertion asSentence In+hDAF-transgenic+pig+hearts+perfused+with+unmodified+human+blood+the+subendocardial%2Fsubepicardial+blood+flow+ratio+changed+in+favor+of+the+subepicardium. assertion.
- assertion asSentence DAF+and+MCP+regulate+cell+survival+of+human+cervical+cancer+cells. assertion.
- assertion asSentence Expression+of+dominant-negative+and+constitutively+active+death-associated+protein+kinase+%28DAPK%29+selectively+inhibits+T+cell+receptor-activated+NF-kappaB+and+T+cell+activation. assertion.
- assertion asSentence DAPK-ZIPK-L13a+axis+forms+a+unique+regulatory+module+that+first+represses%2C+then+repermits+inflammatory+gene+expression. assertion.
- assertion asSentence Hypermethylation+of+DAPK+is+associated+with+cholangiocarcinoma. assertion.
- assertion asSentence Daxx+is+SUMOylated+by+HCMV+pp71. assertion.
- assertion asSentence No+major+involvement+of+the+DBH+gene+in+schizophrenia+in+the+Swedish+population+investigated. assertion.
- assertion asSentence DCC+in+both+commissural+neurons+and+immortalized+cells%2C+is+partially+associated+with+cholesterol-+and+sphingolipid-enriched+membrane+domains+named+lipid+rafts. assertion.
- assertion asSentence Crystal+structures+of+a+deoxycytidine+kinase+variant+lacking+a+flexible+insert+%28residues+65-79%29+reveal+major+changes+in+the+donor+base+binding+loop+%28residues+240-247%29+between+UDP-bound+and+ADP-bound+forms%2C+involving+significant+main-chain+rearrangement. assertion.
- assertion asSentence High+deoxycytidine+kinase+is+associated+with+response+to+pemetrexed-gemcitabine+combination+in+patients+with+advanced+non-small+cell+lung+cancer. assertion.
- assertion asSentence High+levels+of+dCK+in+pancreatic+ductal+adenocarcinoma+predict+longer+survival+times+in+patients+treated+with+adjuvant+gemcitabine. assertion.
- assertion asSentence The+antimyeloma+effect+of+decorin+involved+direct+induction+of+apoptosis+and+activation+of+p21%28WAF%29. assertion.
- assertion asSentence Expression+of+decorin+in+healthy+human+breast+tissue+during+menstrual+cycle. assertion.
- assertion asSentence Vasomotor+properties+are+influenced+by+the+I%2FD+polymorphism+of+the+ACE+gene. assertion.
- assertion asSentence The+I+allele+of+the+ACE+D%2FI+polymorphism+is+associated+with+an+increased+risk+of+late-onset+Alzheimer%27s+disease. assertion.
- assertion asSentence A+high+sodium+intake+strengthens+the+association+of+ACE+I%2FD+polymorphism+with+blood+pressure+levels+in+community-based+samples. assertion.
- assertion asSentence Polymorphism+is+associated+with+whole-body+insulin+sensitivity+and+with+impaired+glucose+tolerance+in+a+healthy+population. assertion.
- assertion asSentence The+I%2F+D+polymorphism+in+the+ACE+gene+is+not+associated+with+generalized+vitiligo+susceptibility+in+a+Gujarat%2C+India+population. assertion.
- assertion asSentence ACEi+therapy+saved+more+costs+and+more+health+gains+in+the+ACE+DD+genotype+than+in+the+ACE+II%2FID+genotype. assertion.
- assertion asSentence The+D+%28deletion%29+allele+of+the+ACE+gene+is+a+risk+factor+for+aortic+dissection+. assertion.
- assertion asSentence ACE+gene+polymorphism+is+associated+with+diabetic+retinopathy. assertion.
- assertion asSentence No+significant+associations+between+ACE+polymorphisms%2C+gene+haplotypes+and+risk+of+endometriosis. assertion.
- assertion asSentence ACE+polymorphism+play+an+important+role+of+the+development+of+respiratory+distress+syndrome+and+bronchopulmonary+dysplasia+in+premature+infants. assertion.
- assertion asSentence Regulation+of+dynactin+through+the+differential+expression+of+p150Glued+isoforms. assertion.
- assertion asSentence DCTN1+subunit+p150Glued+isoforms+notable+for+differential+interaction+with+microtubules. assertion.
- assertion asSentence Human+AKR1C+enzymatic+activity+plays+crucial+roles+on+induction+of+neoplastic+transformation+of+mouse+NIH3T3+cells. assertion.
- assertion asSentence Role+of+AKR1C1in+the+metabolism+of+testosterone+and+progesterone+via+the+5beta-reductase+pathway. assertion.
- assertion asSentence DEAD-box+RNA+helicase+p68+is+not+required+for+nuclear+translocation+of+beta-catenin+in+colon+cancer+cells. assertion.
- assertion asSentence Crystal+structure+of+HD6. assertion.
- assertion asSentence Houttuynia+Cordata+can+up-regulate+expression+of+HBD-2+mRNA+in+SPC-A-1+pulmonary+epithelial+cells. assertion.
- assertion asSentence Avocado+sugars+%28AV119%29+activate+keratinocyte+protein+kinase+C+and+protein+tyrosine+kinases%2C+leading+to+AP-1+and+HBD-2+gene+activation. assertion.
- assertion asSentence MDM2+regulates+dihydrofolate+reductase+activity+through+monoubiquitination. assertion.
- assertion asSentence NQO1+genotype+is+a+prognostic+and+predictive+marker+for+breast+cancer. assertion.
- assertion asSentence In+endoplasmic+reticulum%2C+degradation+proceeds+via+an+association+with+UBC7. assertion.
- assertion asSentence The+commonly+occurring+Thr92Ala+D2+variant+is+associated+with+a+decreased+rate+of+acute+TSH-stimulated+T3+release+from+the+thyroid+consistent+with+a+decrease+in+intrathyroidal+deiodination. assertion.
- assertion asSentence TGF-beta+stimulates+transcription+of+the+hDio3+gene+via+a+Smad-dependent+pathway. assertion.
- assertion asSentence Significantly+higher+DKC1+mRNA+is+associated+with+colorectal+cancer. assertion.
- assertion asSentence The+glycoforms+of+saliva+and+lung+gp-340+mediated+differential+aggregation+of+Le%28b%29-+%28Helicobacter+pylori%29%2C+sialylpolylactosamine-+%28Streptococcus+suis%29+or+sialic+acid-+%28Streptococcus+mutans%29+binding+bacteria. assertion.
- assertion asSentence Dystrophinopathy+is+an+important+cause+of+LGMD+phenotype+in+girls+and+should+be+considered+in+the+differential+diagnosis. assertion.
- assertion asSentence Two+mutations+in+middle+domain%2C+R361S+and+R399A%2C+disrupt+the+tetrameric+structure+of+dynamin+in+the+unassembled+state+and+impair+its+ability+to+stably+bind+to+and+nucleate+higher-order+self-assembly+on+membranes. assertion.
- assertion asSentence DNase1L2+plays+an+essential+role+in+DNA+degradation+during+terminal+differentiation+of+epidermal+KC. assertion.
- assertion asSentence NDE1+and+NDEL1+act+upstream+of+LIS1+in+dynein+recruitment%2C+and%2For+activation%2C+on+the+membrane. assertion.
- assertion asSentence DNM2+reglates+riboflavin+endocytosis+in+human+placental+trophoblasts. assertion.
- assertion asSentence Phosphorylation+of+dynamin+II+primarily+occurs+on+a+single+site+that+regulates+cytokinesis+downstream+of+calcineurin%2C+rather+than+regulating+endocytosis+or+centrosome+function. assertion.
- assertion asSentence In+hepatocellular+carcinoma%2C+DNMT1+is+necessary+to+maintain+the+methylation+of+CpG+islands+in+certain+tumor-related+genes. assertion.