Matches in Nanopublications for { <http://bio2rdf.org/drugbank:DB00412> ?p ?o ?g. }
Showing items 1 to 35 of
35
with 100 items per page.
- drugbank:DB00412 type drugbank_vocabulary:Drug assertion.
- drugbank:DB00412 label "Rosiglitazone [drugbank:DB00412]" assertion.
- drugbank:DB00412 seeAlso DB00412 assertion.
- drugbank:DB00412 seeAlso rosiglitazone.html assertion.
- drugbank:DB00412 seeAlso cx1532.shtml assertion.
- drugbank:DB00412 seeAlso rosigl.htm assertion.
- drugbank:DB00412 identifier "drugbank:DB00412" assertion.
- drugbank:DB00412 description "Rosiglitazone is an anti-diabetic drug in the thiazolidinedione class of drugs. It is marketed by the pharmaceutical company GlaxoSmithKline as a stand-alone drug (Avandia) and in combination with metformin (Avandamet) or with glimepiride (Avandaryl). Like other thiazolidinediones, the mechanism of action of rosiglitazone is by activation of the intracellular receptor class of the peroxisome proliferator-activated receptors (PPARs), specifically PPARγ. Rosiglitazone is a selective ligand of PPARγ, and has no PPARα-binding action. Apart from its effect on insulin resistance, it appears to have an anti-inflammatory effect: nuclear factor kappa-B (NFκB) levels fall and inhibitor (IκB) levels increase in patients on rosiglitazone. Recent research has suggested that rosiglitazone may also be of benefit to a subset of patients with Alzheimer's disease not expressing the ApoE4 allele. This is the subject of a clinical trial currently underway." assertion.
- drugbank:DB00412 title "Rosiglitazone" assertion.
- drugbank:DB00412 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00412_DB01026 assertion.
- drugbank:DB00412 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00412_DB01045 assertion.
- drugbank:DB00412 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00412_DB00930 assertion.
- drugbank:DB00412 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00412_DB06237 assertion.
- drugbank:DB00412 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00052_DB00412 assertion.
- drugbank:DB00412 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00412_DB01241 assertion.
- drugbank:DB00412 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00412_DB00755 assertion.
- drugbank:DB00412 bio2rdf_vocabulary:identifier "DB00412" assertion.
- drugbank:DB00412 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB00412 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB00412" assertion.
- drugbank:DB00412 bio2rdf_vocabulary:x-identifiers.org DB00412 assertion.
- drugbank:DB00412 drugbank_vocabulary:drugbank-id "APRD00403" assertion.
- drugbank:DB00412 drugbank_vocabulary:drugbank-id "DB00412" assertion.
- drugbank:DB00412 drugbank_vocabulary:x-cas cas:122320-73-4 assertion.
- drugbank:DB00412 drugbank_vocabulary:x-pdb pdb:BRL assertion.
- drugbank:DB00412 drugbank_vocabulary:x-ahfs ahfs:68:20.28 assertion.
- drugbank:DB00412 drugbank_vocabulary:x-atc atc:A10BG02 assertion.
- drugbank:DB00412 drugbank_vocabulary:x-chebi chebi:50122 assertion.
- drugbank:DB00412 drugbank_vocabulary:x-dpd dpd:2241113 assertion.
- drugbank:DB00412 drugbank_vocabulary:x-kegg kegg:D00596 assertion.
- drugbank:DB00412 drugbank_vocabulary:x-pharmgkb pharmgkb:PA451283 assertion.
- drugbank:DB00412 drugbank_vocabulary:x-wikipedia wikipedia:Rosiglitazone assertion.
- drugbank:DB00412 drugbank_vocabulary:x-bindingdb bindingdb:28681 assertion.
- drugbank:DB00412 drugbank_vocabulary:x-ndc ndc:0029-3158-18 assertion.
- drugbank:DB00412 drugbank_vocabulary:x-gtp gtp:1056 assertion.
- drugbank:DB00412 drugbank_vocabulary:x-iuphar iuphar:1056 assertion.