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Matches in Nanopublications for { <http://bio2rdf.org/drugbank:DB00672> ?p ?o ?g. }

• drugbank:DB00672 type drugbank_vocabulary:Drug assertion.
• drugbank:DB00672 label "Chlorpropamide [drugbank:DB00672]" assertion.
• drugbank:DB00672 seeAlso DB00672 assertion.
• drugbank:DB00672 seeAlso chlorpropamide.html assertion.
• drugbank:DB00672 seeAlso chlorpro.htm assertion.
• drugbank:DB00672 identifier "drugbank:DB00672" assertion.
• drugbank:DB00672 description "Chlorpropamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin. Sulfonylureas increase both basal insulin secretion and meal-stimulated insulin release. Medications in this class differ in their dose, rate of absorption, duration of action, route of elimination and binding site on their target pancreatic β cell receptor. Sulfonylureas also increase peripheral glucose utilization, decrease hepatic gluconeogenesis and may increase the number and sensitivity of insulin receptors. Sulfonylureas are associated with weight gain, though less so than insulin. Due to their mechanism of action, sulfonylureas may cause hypoglycemia and require consistent food intake to decrease this risk. The risk of hypoglycemia is increased in elderly, debilitated and malnourished individuals. Chlorpropamide is not recommended for the treatment of NIDDM as it increases blood pressure and the risk of retinopathy (UKPDS-33). Up to 80% of the single oral dose of chlorpropramide is metabolized, likely in the liver; 80-90% of the dose is excreted in urine as unchanged drug and metabolites. Renal and hepatic dysfunction may increase the risk of hypoglycemia." assertion.
• drugbank:DB00672 title "Chlorpropamide" assertion.
• drugbank:DB00672 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00672_DB01015 assertion.
• drugbank:DB00672 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00672_DB01295 assertion.
• drugbank:DB00672 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00636_DB00672 assertion.
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• drugbank:DB00672 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00672_DB01401 assertion.
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• drugbank:DB00672 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00672_DB00945 assertion.
• drugbank:DB00672 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00359_DB00672 assertion.
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• drugbank:DB00672 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00672_DB01298 assertion.
• drugbank:DB00672 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00672_DB01582 assertion.
• drugbank:DB00672 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00052_DB00672 assertion.
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• drugbank:DB00672 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00263_DB00672 assertion.
• drugbank:DB00672 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00672_DB01297 assertion.
• drugbank:DB00672 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00672_DB00891 assertion.
• drugbank:DB00672 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00672_DB00960 assertion.
• drugbank:DB00672 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00521_DB00672 assertion.
• drugbank:DB00672 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00672_DB00812 assertion.
• drugbank:DB00672 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00672_DB01399 assertion.
• drugbank:DB00672 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00672_DB01193 assertion.
• drugbank:DB00672 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00264_DB00672 assertion.
• drugbank:DB00672 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00489_DB00672 assertion.
• drugbank:DB00672 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00672_DB01136 assertion.
• drugbank:DB00672 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00672_DB01045 assertion.
• drugbank:DB00672 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00612_DB00672 assertion.
• drugbank:DB00672 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00672_DB00795 assertion.
• drugbank:DB00672 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00598_DB00672 assertion.
• drugbank:DB00672 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00672_DB01581 assertion.
• drugbank:DB00672 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00672_DB01203 assertion.
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• drugbank:DB00672 bio2rdf_vocabulary:identifier "DB00672" assertion.
• drugbank:DB00672 bio2rdf_vocabulary:namespace "drugbank" assertion.
• drugbank:DB00672 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB00672" assertion.
• drugbank:DB00672 bio2rdf_vocabulary:x-identifiers.org DB00672 assertion.
• drugbank:DB00672 drugbank_vocabulary:drugbank-id "APRD00029" assertion.
• drugbank:DB00672 drugbank_vocabulary:drugbank-id "DB00672" assertion.
• drugbank:DB00672 drugbank_vocabulary:x-cas cas:94-20-2 assertion.
• drugbank:DB00672 drugbank_vocabulary:x-chemspider chemspider:2626 assertion.
• drugbank:DB00672 drugbank_vocabulary:x-pubchemcompound pubchem.compound:2727 assertion.
• drugbank:DB00672 drugbank_vocabulary:x-pubchemsubstance pubchem.substance:46506402 assertion.
• drugbank:DB00672 drugbank_vocabulary:x-ahfs ahfs:68:20.20 assertion.
• drugbank:DB00672 drugbank_vocabulary:x-atc atc:A10BB02 assertion.
• drugbank:DB00672 drugbank_vocabulary:x-chebi chebi:3650 assertion.
• drugbank:DB00672 drugbank_vocabulary:x-dpd dpd:156728 assertion.
• drugbank:DB00672 drugbank_vocabulary:x-kegg kegg:D00271 assertion.
• drugbank:DB00672 drugbank_vocabulary:x-pharmgkb pharmgkb:PA448966 assertion.
• drugbank:DB00672 drugbank_vocabulary:x-wikipedia wikipedia:Chlorpropamide assertion.
• drugbank:DB00672 drugbank_vocabulary:x-ndc ndc:0378-0197-01 assertion.