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- drugbank:DB01426 type drugbank_vocabulary:Drug assertion.
- drugbank:DB01426 label "Ajmaline [drugbank:DB01426]" assertion.
- drugbank:DB01426 seeAlso DB01426 assertion.
- drugbank:DB01426 identifier "drugbank:DB01426" assertion.
- drugbank:DB01426 description "An alkaloid found in the root of Rauwolfia serpentina, among other plant sources. It is a class Ia antiarrhythmic agent that apparently acts by changing the shape and threshold of cardiac action potentials. Ajmaline produces potent sodium channel blocking effects and a very short half-life which makes it a very useful drug for acute intravenous treatments. The drug has been very popular in some countries for the treatment of atrial fibrillation in patients with the Wolff–Parkinson–White syndrome and in well tolerated monomorphic ventricular tachycardias. It has also been used for many years as a drug to challenge the conduction system of the heart in cases of bundle branch block and syncope. In these cases, abnormal prolongation of the HV interval has been taken as a proof for infrahisian conduction defects tributary for permanent pacemaker implantation." assertion.
- drugbank:DB01426 title "Ajmaline" assertion.
- drugbank:DB01426 bio2rdf_vocabulary:identifier "DB01426" assertion.
- drugbank:DB01426 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB01426 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB01426" assertion.
- drugbank:DB01426 bio2rdf_vocabulary:x-identifiers.org DB01426 assertion.
- drugbank:DB01426 drugbank_vocabulary:drugbank-id "DB01426" assertion.
- drugbank:DB01426 drugbank_vocabulary:x-cas cas:4360-12-7 assertion.
- drugbank:DB01426 drugbank_vocabulary:x-atc atc:C01BA05 assertion.
- drugbank:DB01426 drugbank_vocabulary:x-chebi chebi:28462 assertion.
- drugbank:DB01426 drugbank_vocabulary:x-kegg kegg:C06542 assertion.
- drugbank:DB01426 drugbank_vocabulary:x-kegg kegg:D00199 assertion.
- drugbank:DB01426 drugbank_vocabulary:x-pharmgkb pharmgkb:PA164776839 assertion.
- drugbank:DB01426 drugbank_vocabulary:x-wikipedia wikipedia:Ajmaline assertion.