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- drugbank:DB01622 type drugbank_vocabulary:Drug assertion.
- drugbank:DB01622 label "Thioproperazine [drugbank:DB01622]" assertion.
- drugbank:DB01622 seeAlso DB01622 assertion.
- drugbank:DB01622 identifier "drugbank:DB01622" assertion.
- drugbank:DB01622 description "Thioproperazine is a potent neuroleptic with antipsychotic properties. Thioproperazine has a marked cataleptic and antiapomorphine activity associated with relatively slight sedative, hypothermic and spasmolytic effects. It is virtually without antiserotonin and hypotensive action and has no antihistaminic property. It is used for the treatment of all types of acute and chronic schizophrenia, including those which did not respond to the usual neuroleptics; manic syndromes. Overdosage may result in severe extrapyramidal symptoms with dysphagia, marked sialorrhea, persistent and rapidly increasing hyperthermia, pulmonary syndrome, state of shock with pallor and profuse sweating, which may be followed by collapse and coma. LD50 in mice is 70 mg/kg I.V., 120 mg/kg I.P., 500 mg/kg S.C. and 830 mg/kg P.O." assertion.
- drugbank:DB01622 title "Thioproperazine" assertion.
- drugbank:DB01622 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00674_DB01622 assertion.
- drugbank:DB01622 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00989_DB01622 assertion.
- drugbank:DB01622 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00843_DB01622 assertion.
- drugbank:DB01622 drugbank_vocabulary:food-interaction drugbank_resource:af8b270e785fb3df171ebbe1ee92ac4f assertion.
- drugbank:DB01622 bio2rdf_vocabulary:identifier "DB01622" assertion.
- drugbank:DB01622 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB01622 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB01622" assertion.
- drugbank:DB01622 bio2rdf_vocabulary:x-identifiers.org DB01622 assertion.
- drugbank:DB01622 drugbank_vocabulary:drugbank-id "DB01622" assertion.
- drugbank:DB01622 drugbank_vocabulary:x-cas cas:316-81-4 assertion.
- drugbank:DB01622 drugbank_vocabulary:x-chemspider chemspider:9058 assertion.
- drugbank:DB01622 drugbank_vocabulary:x-pubchemcompound pubchem.compound:9429 assertion.
- drugbank:DB01622 drugbank_vocabulary:x-pubchemsubstance pubchem.substance:46507111 assertion.
- drugbank:DB01622 drugbank_vocabulary:x-atc atc:N05AB08 assertion.
- drugbank:DB01622 drugbank_vocabulary:x-chebi chebi:59120 assertion.
- drugbank:DB01622 drugbank_vocabulary:x-dpd dpd:1927639 assertion.
- drugbank:DB01622 drugbank_vocabulary:x-kegg kegg:D08585 assertion.
- drugbank:DB01622 drugbank_vocabulary:x-pharmgkb pharmgkb:PA164754875 assertion.