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- drugbank:DB04876 type drugbank_vocabulary:Drug assertion.
- drugbank:DB04876 label "Vildagliptin [drugbank:DB04876]" assertion.
- drugbank:DB04876 seeAlso DB04876 assertion.
- drugbank:DB04876 identifier "drugbank:DB04876" assertion.
- drugbank:DB04876 description "Vildagliptin, previously identified as LAF237, is a new oral anti-hyperglycemic agent (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Vildagliptin inhibits the inactivation of GLP-1 and GIP by DPP-4, allowing GLP-1 and GIP to potentiate the secretion of insulin in the beta cells and suppress glucaon release by the alpha cells of the islets of Langerhans in the pancreas. It is currently in clinical trials in the U.S. and has been shown to reduce hyperglycemia in type 2 diabetes mellitus. While the drug is still not approved for use in the US, it was approved in Feb 2008 by European Medicines Agency for use within the EU and is listed on the Australian PBS with certain restrictions." assertion.
- drugbank:DB04876 title "Vildagliptin" assertion.
- drugbank:DB04876 bio2rdf_vocabulary:identifier "DB04876" assertion.
- drugbank:DB04876 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB04876 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB04876" assertion.
- drugbank:DB04876 bio2rdf_vocabulary:x-identifiers.org DB04876 assertion.
- drugbank:DB04876 drugbank_vocabulary:drugbank-id "DB04876" assertion.
- drugbank:DB04876 drugbank_vocabulary:x-cas cas:274901-16-5 assertion.
- drugbank:DB04876 drugbank_vocabulary:x-chemspider chemspider:5293734 assertion.
- drugbank:DB04876 drugbank_vocabulary:x-pubchemcompound pubchem.compound:6918537 assertion.
- drugbank:DB04876 drugbank_vocabulary:x-pubchemsubstance pubchem.substance:99443227 assertion.
- drugbank:DB04876 drugbank_vocabulary:x-atc atc:A10BH02 assertion.
- drugbank:DB04876 drugbank_vocabulary:x-pharmgkb pharmgkb:PA165958346 assertion.
- drugbank:DB04876 drugbank_vocabulary:x-wikipedia wikipedia:Vildagliptin assertion.
- drugbank:DB04876 drugbank_vocabulary:x-bindingdb bindingdb:11695 assertion.