Matches in Nanopublications for { <http://bio2rdf.org/drugbank:DB06594> ?p ?o ?g. }
Showing items 1 to 19 of
19
with 100 items per page.
- drugbank:DB06594 type drugbank_vocabulary:Drug assertion.
- drugbank:DB06594 label "Agomelatine [drugbank:DB06594]" assertion.
- drugbank:DB06594 seeAlso DB06594 assertion.
- drugbank:DB06594 identifier "drugbank:DB06594" assertion.
- drugbank:DB06594 description "Agomelatine is structurally closely related to melatonin. Agomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors, tested in an animal model of depression. Agomelatine was discovered and developed by the European pharmaceutical company Servier Laboratories Ltd. Servier continue to develop the drug and conduct phase III trials in the European Union. In 2005 Servier submitted Agomelatine to the European Medicines Agency (EMEA). On 27 July 2006 the Committee for Medical Products for Human Use (CHMP) of the EMEA recommended a refusal of the marketing authorisation of Valdoxan/Thymanax. The major concern was that efficacy had not been sufficiently shown. In 2006 Servier sold the rights to develop Agomelatine in the US to Novartis. The development for the US market was discontinued in October 2011. It is currently sold in Australia under the Valdoxan trade name." assertion.
- drugbank:DB06594 title "Agomelatine" assertion.
- drugbank:DB06594 bio2rdf_vocabulary:identifier "DB06594" assertion.
- drugbank:DB06594 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB06594 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB06594" assertion.
- drugbank:DB06594 bio2rdf_vocabulary:x-identifiers.org DB06594 assertion.
- drugbank:DB06594 drugbank_vocabulary:drugbank-id "DB06594" assertion.
- drugbank:DB06594 drugbank_vocabulary:x-cas cas:138112-76-2 assertion.
- drugbank:DB06594 drugbank_vocabulary:x-chemspider chemspider:74141 assertion.
- drugbank:DB06594 drugbank_vocabulary:x-pubchemcompound pubchem.compound:82148 assertion.
- drugbank:DB06594 drugbank_vocabulary:x-atc atc:N06AX22 assertion.
- drugbank:DB06594 drugbank_vocabulary:x-kegg kegg:D02578 assertion.
- drugbank:DB06594 drugbank_vocabulary:x-pharmgkb pharmgkb:PA165958363 assertion.
- drugbank:DB06594 drugbank_vocabulary:x-wikipedia wikipedia:Agomelatine assertion.
- drugbank:DB06594 drugbank_vocabulary:x-bindingdb bindingdb:50035179 assertion.