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- drugbank_resource:DB00257_DB01394 type drugbank_vocabulary:Drug-Drug-Interaction assertion.
- drugbank_resource:DB00257_DB01394 label "DDI between Clotrimazole and Colchicine - CYP3A4 Inhibitors (Moderate) such as clotrimazole may increase the serum concentration of colchicine. Reduce colchicine dose (for gout flares: to 1.2 mg x 1 dose, with next dose no sooner than 3 days later; for Familial Mediterranean Fever: to no more than 1.2 mg/day) when using in combination with a moderate CYP3A4 inhibitor such as erythromycin or verapamil. Increase monitoring for colchicine-related toxicity when using such combinations. Use extra caution in patients with impaired renal and/or hepatic function. [drugbank_resource:DB00257_DB01394]" assertion.
- drugbank_resource:DB00257_DB01394 identifier "drugbank_resource:DB00257_DB01394" assertion.
- drugbank_resource:DB00257_DB01394 title "DDI between Clotrimazole and Colchicine - CYP3A4 Inhibitors (Moderate) such as clotrimazole may increase the serum concentration of colchicine. Reduce colchicine dose (for gout flares: to 1.2 mg x 1 dose, with next dose no sooner than 3 days later; for Familial Mediterranean Fever: to no more than 1.2 mg/day) when using in combination with a moderate CYP3A4 inhibitor such as erythromycin or verapamil. Increase monitoring for colchicine-related toxicity when using such combinations. Use extra caution in patients with impaired renal and/or hepatic function." assertion.