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- drugbank_resource:DB00448_DB06616 type drugbank_vocabulary:Drug-Drug-Interaction assertion.
- drugbank_resource:DB00448_DB06616 label "DDI between Lansoprazole and Bosutinib - Concomitant lansoprazole (PPI) decreased bosutinib Cmax by 46% and AUC by 26% compared to bosutinib alone. Consider using short-acting antacids or H2 blockers instead of PPIs to avoid a reduction in bosutinib exposure. Separate antacid or H2 blocker dosing and BOSULIF dosing by more than 2 hours. [drugbank_resource:DB00448_DB06616]" assertion.
- drugbank_resource:DB00448_DB06616 identifier "drugbank_resource:DB00448_DB06616" assertion.
- drugbank_resource:DB00448_DB06616 title "DDI between Lansoprazole and Bosutinib - Concomitant lansoprazole (PPI) decreased bosutinib Cmax by 46% and AUC by 26% compared to bosutinib alone. Consider using short-acting antacids or H2 blockers instead of PPIs to avoid a reduction in bosutinib exposure. Separate antacid or H2 blocker dosing and BOSULIF dosing by more than 2 hours." assertion.