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- drugbank_resource:DB00726_DB01149 type drugbank_vocabulary:Drug-Drug-Interaction assertion.
- drugbank_resource:DB00726_DB01149 label "DDI between Trimipramine and Nefazodone - Increased risk of serotonin syndrome. Monitor for symptoms of serotonin syndrome. Nefazodone, a strong CYP3A4 inhibitor, may also decrease the metabolism and clearance of Trimipramine, a CYP3A4 substrate. Consider alternate therapy or monitor for changes in therapeutic and adverse effects of Trimipramine if Nefazodone is initiated, discontinued or dose changed. [drugbank_resource:DB00726_DB01149]" assertion.
- drugbank_resource:DB00726_DB01149 identifier "drugbank_resource:DB00726_DB01149" assertion.
- drugbank_resource:DB00726_DB01149 title "DDI between Trimipramine and Nefazodone - Increased risk of serotonin syndrome. Monitor for symptoms of serotonin syndrome. Nefazodone, a strong CYP3A4 inhibitor, may also decrease the metabolism and clearance of Trimipramine, a CYP3A4 substrate. Consider alternate therapy or monitor for changes in therapeutic and adverse effects of Trimipramine if Nefazodone is initiated, discontinued or dose changed." assertion.