Matches in Nanopublications for { <http://purl.org/np/RA2plesgmHbxVeX02hRRQwCqTxProxTT8hq58ZwtSfWok#association> ?p ?o ?g. }
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- association type Statement assertion.
- association label "The nicotinic-acetylcholine receptor (nAchR)- antagonist mecamylanine has been found to reduce the stimulus produced by ethanol in human lab studies. The nAchR-antagonist varenicline has also displayed positive effect in reducing alcohol consumption in multiple clinical trials. In this 12- week double-blind trial, participants (n 1⁄4 126) were randomized to either mecamylamine (10 mg daily) or placebo. No medication effect was found for reducing heavy drinking days (HDD) or alcohol craving. Smoking status had no effect on the results. The authors suggest that broad-spectrum nAchR-antagonists may not be beneficial in treat- ing AUD" assertion.
- association object MONDO_0002046 assertion.
- association predicate treats assertion.
- association subject DRUGBANK:DB00657 assertion.
- association relation OffLabelIndication assertion.
- association publications 30973369 assertion.
- association provided_by NeuroDKG assertion.