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- NP665979.RABd7s-QvvpFR-f1-gFPzkS4LwQ4AUTiZt5iM9xV0xyLU130_assertion type Assertion NP665979.RABd7s-QvvpFR-f1-gFPzkS4LwQ4AUTiZt5iM9xV0xyLU130_head.
- NP665979.RABd7s-QvvpFR-f1-gFPzkS4LwQ4AUTiZt5iM9xV0xyLU130_assertion description "[Here we show that although several mouse brain structures were infected, they exhibited a differential pattern in terms of MMP, TIMP, and cytokine expression, exemplified by (i) a large increase in pro-MMP9 levels, in particular in the hippocampus, which occurred mainly in neurons and was associated with in situ gelatinolytic activity, (ii) specific and significant upregulation of MT1-MMP mRNA expression in the cortex and hypothalamus, (iii) an MMP/TIMP imbalance, suggested by the upregulation of TIMP-1 mRNA in the cortex, hippocampus, and hypothalamus and of TIMP-3 mRNA in the cortex, and (iv) a concomitant region-specific large increase in expression of Th1-like cytokines, such as gamma interferon, tumor necrosis factor alpha, and interleukin 6 (IL-6), contrasting with weaker induction of Th2-like cytokines, such as IL-4 and IL-10.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP665979.RABd7s-QvvpFR-f1-gFPzkS4LwQ4AUTiZt5iM9xV0xyLU130_provenance.
- NP665979.RABd7s-QvvpFR-f1-gFPzkS4LwQ4AUTiZt5iM9xV0xyLU130_assertion evidence source_evidence_literature NP665979.RABd7s-QvvpFR-f1-gFPzkS4LwQ4AUTiZt5iM9xV0xyLU130_provenance.
- NP665979.RABd7s-QvvpFR-f1-gFPzkS4LwQ4AUTiZt5iM9xV0xyLU130_assertion SIO_000772 11483772 NP665979.RABd7s-QvvpFR-f1-gFPzkS4LwQ4AUTiZt5iM9xV0xyLU130_provenance.
- NP665979.RABd7s-QvvpFR-f1-gFPzkS4LwQ4AUTiZt5iM9xV0xyLU130_assertion wasDerivedFrom befree-20140225 NP665979.RABd7s-QvvpFR-f1-gFPzkS4LwQ4AUTiZt5iM9xV0xyLU130_provenance.
- NP665979.RABd7s-QvvpFR-f1-gFPzkS4LwQ4AUTiZt5iM9xV0xyLU130_assertion wasGeneratedBy ECO_0000203 NP665979.RABd7s-QvvpFR-f1-gFPzkS4LwQ4AUTiZt5iM9xV0xyLU130_provenance.