Matches in Nanopublications for { <http://rdf.disgenet.org/nanopublications.trig#NP699321.RACj-HTgX2AJq-JCfERMBERcdv0z3NT5mk3ePDFNLejXM130_assertion> ?p ?o ?g. }
Showing items 1 to 6 of
6
with 100 items per page.
- NP699321.RACj-HTgX2AJq-JCfERMBERcdv0z3NT5mk3ePDFNLejXM130_assertion type Assertion NP699321.RACj-HTgX2AJq-JCfERMBERcdv0z3NT5mk3ePDFNLejXM130_head.
- NP699321.RACj-HTgX2AJq-JCfERMBERcdv0z3NT5mk3ePDFNLejXM130_assertion description "[In this study, we propose a novel function for CD44 using synovial cells from rheumatoid arthritis (RA) patients and demonstrated that CD44 cross-linking augmented Fas expression and subsequent Fas-mediated apoptosis of the cells: 1) cross-linking of CD44 on RA synovial cells markedly augmented Fas expression and its mRNA transcription; 2) engagement of CD44 up-regulated Fas on the cells within 3 h, much more than IL-1beta and TNF-alpha did; 3) the Fas-mediated early apoptotic change of the cells was amplified by CD44 cross-linking; and 4) hyaluronan, especially when fragmented, also augmented Fas-mediated early apoptosis of the cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP699321.RACj-HTgX2AJq-JCfERMBERcdv0z3NT5mk3ePDFNLejXM130_provenance.
- NP699321.RACj-HTgX2AJq-JCfERMBERcdv0z3NT5mk3ePDFNLejXM130_assertion evidence source_evidence_literature NP699321.RACj-HTgX2AJq-JCfERMBERcdv0z3NT5mk3ePDFNLejXM130_provenance.
- NP699321.RACj-HTgX2AJq-JCfERMBERcdv0z3NT5mk3ePDFNLejXM130_assertion SIO_000772 11466334 NP699321.RACj-HTgX2AJq-JCfERMBERcdv0z3NT5mk3ePDFNLejXM130_provenance.
- NP699321.RACj-HTgX2AJq-JCfERMBERcdv0z3NT5mk3ePDFNLejXM130_assertion wasDerivedFrom befree-20140225 NP699321.RACj-HTgX2AJq-JCfERMBERcdv0z3NT5mk3ePDFNLejXM130_provenance.
- NP699321.RACj-HTgX2AJq-JCfERMBERcdv0z3NT5mk3ePDFNLejXM130_assertion wasGeneratedBy ECO_0000203 NP699321.RACj-HTgX2AJq-JCfERMBERcdv0z3NT5mk3ePDFNLejXM130_provenance.