Matches in Nanopublications for { <http://rdf.disgenet.org/nanopublications.trig#NP721908.RAobG2E1vrvK76kDul8Sk0BOsfS32Xwa0OqKypaum2avM130_assertion> ?p ?o ?g. }
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- NP721908.RAobG2E1vrvK76kDul8Sk0BOsfS32Xwa0OqKypaum2avM130_assertion type Assertion NP721908.RAobG2E1vrvK76kDul8Sk0BOsfS32Xwa0OqKypaum2avM130_head.
- NP721908.RAobG2E1vrvK76kDul8Sk0BOsfS32Xwa0OqKypaum2avM130_assertion description "[Psychotropic drugs can meaningfully affect PD risk gene mRNA transcription, including antipsychotics (upregulate dopamine receptors D2 and D3 (DRD2, DRD3); downregulate low-density lipoprotein receptor-related protein 8 (LRP8), ubiquitin carboxyl-terminal esterase L1 (UCHL1, also known as PARK5)), haloperidol (upregulates DRD3, parkin (PRKN, also known as PARK2), DRD2; downregulates brain-derived neurotrophic factor (BDNF)), risperidone (upregulates monoamine oxidase B (MAOB), DRD2), olanzapine (upregulates transmembrane protein 163 (TMEM163), BDNF, glutathione S-transferase mu 1 (GSTM1), MAOB, DRD2, solute carrier organic anion transporter family, member 3A1 (SLCO3A1)), aripiprazole (upregulates DRD2), quetiapine, paliperidone, lurasidone, carbamazepine, and many antidepressants (upregulate BDNF), lithium and bupropion (downregulate BDNF), amitriptyline (upregulates DRD3, DRD2), imipramine (upregulates BDNF, DRD3, DRD2), desipramine (upregulates BDNF, DRD3), and fluoxetine (upregulates acid beta-glucosidase (GBA), coiled-coil domain containing 62 (CCDC62), BDNF, DRD3, UCHL1, unc-13 homolog B (UNC13B), and perhaps huntingtin interacting protein 1 related (HIP1R); downregulates microtubule-associated protein tau (MAPT), methylcrotonoyl-coenzyme A carboxylase I (MCCC1), GSTM1, 28kDa calbindin 1 (CALB1)).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP721908.RAobG2E1vrvK76kDul8Sk0BOsfS32Xwa0OqKypaum2avM130_provenance.
- NP721908.RAobG2E1vrvK76kDul8Sk0BOsfS32Xwa0OqKypaum2avM130_assertion evidence source_evidence_literature NP721908.RAobG2E1vrvK76kDul8Sk0BOsfS32Xwa0OqKypaum2avM130_provenance.
- NP721908.RAobG2E1vrvK76kDul8Sk0BOsfS32Xwa0OqKypaum2avM130_assertion SIO_000772 22507762 NP721908.RAobG2E1vrvK76kDul8Sk0BOsfS32Xwa0OqKypaum2avM130_provenance.
- NP721908.RAobG2E1vrvK76kDul8Sk0BOsfS32Xwa0OqKypaum2avM130_assertion wasDerivedFrom befree-20140225 NP721908.RAobG2E1vrvK76kDul8Sk0BOsfS32Xwa0OqKypaum2avM130_provenance.
- NP721908.RAobG2E1vrvK76kDul8Sk0BOsfS32Xwa0OqKypaum2avM130_assertion wasGeneratedBy ECO_0000203 NP721908.RAobG2E1vrvK76kDul8Sk0BOsfS32Xwa0OqKypaum2avM130_provenance.