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- NP1207998.RAC9_yROTARSYt8PJ0W2QJEGixu1yaKReTLKcCcKUx0A0130_assertion type Assertion NP1207998.RAC9_yROTARSYt8PJ0W2QJEGixu1yaKReTLKcCcKUx0A0130_head.
- NP1207998.RAC9_yROTARSYt8PJ0W2QJEGixu1yaKReTLKcCcKUx0A0130_assertion description "[However, the resistant cells were found to secrete high levels of IGF-I. ii) Presence of exogenous IGF-I promoted cell proliferation, which decreased when an inhibitor of IGF-IR (picropodophyllin, PPP) was added. iii) BMH and IGF-I are both involved in the regulation of genes of the ATP binding cassette (ABC) related to resistance development (MDR1, MRP1, MRP2, MRP3 and BCRP). iv) The levels of ABC gene expression by leukemia cells were found to increase in the presence of increasing numbers of BMH.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP1207998.RAC9_yROTARSYt8PJ0W2QJEGixu1yaKReTLKcCcKUx0A0130_provenance.
- NP1207998.RAC9_yROTARSYt8PJ0W2QJEGixu1yaKReTLKcCcKUx0A0130_assertion evidence source_evidence_literature NP1207998.RAC9_yROTARSYt8PJ0W2QJEGixu1yaKReTLKcCcKUx0A0130_provenance.
- NP1207998.RAC9_yROTARSYt8PJ0W2QJEGixu1yaKReTLKcCcKUx0A0130_assertion SIO_000772 25095896 NP1207998.RAC9_yROTARSYt8PJ0W2QJEGixu1yaKReTLKcCcKUx0A0130_provenance.
- NP1207998.RAC9_yROTARSYt8PJ0W2QJEGixu1yaKReTLKcCcKUx0A0130_assertion wasDerivedFrom befree-2016 NP1207998.RAC9_yROTARSYt8PJ0W2QJEGixu1yaKReTLKcCcKUx0A0130_provenance.
- NP1207998.RAC9_yROTARSYt8PJ0W2QJEGixu1yaKReTLKcCcKUx0A0130_assertion wasGeneratedBy ECO_0000203 NP1207998.RAC9_yROTARSYt8PJ0W2QJEGixu1yaKReTLKcCcKUx0A0130_provenance.