Matches in Nanopublications for { <http://rdf.disgenet.org/resource/nanopub/NP1217047.RA-lUgxOZ6PsbZ_AAIpKf1f3Yi_2sLfq6N53ZAfsfuym4130_assertion> ?p ?o ?g. }
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- NP1217047.RA-lUgxOZ6PsbZ_AAIpKf1f3Yi_2sLfq6N53ZAfsfuym4130_assertion type Assertion NP1217047.RA-lUgxOZ6PsbZ_AAIpKf1f3Yi_2sLfq6N53ZAfsfuym4130_head.
- NP1217047.RA-lUgxOZ6PsbZ_AAIpKf1f3Yi_2sLfq6N53ZAfsfuym4130_assertion description "[Ubc13 was dispensable for transforming growth factor ? (TGF?)-induced SMAD activation but was required for activation of non-SMAD signaling via TGF?-activating kinase 1 (TAK1) and p38, whose activity controls expression of numerous metastasis promoting genes. p38 activation restored metastatic activity to Ubc13-deficient cells, and its pharmacological inhibition attenuated BCa metastasis in mice, suggesting it is a therapeutic option for metastatic BCa.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP1217047.RA-lUgxOZ6PsbZ_AAIpKf1f3Yi_2sLfq6N53ZAfsfuym4130_provenance.
- NP1217047.RA-lUgxOZ6PsbZ_AAIpKf1f3Yi_2sLfq6N53ZAfsfuym4130_assertion evidence source_evidence_literature NP1217047.RA-lUgxOZ6PsbZ_AAIpKf1f3Yi_2sLfq6N53ZAfsfuym4130_provenance.
- NP1217047.RA-lUgxOZ6PsbZ_AAIpKf1f3Yi_2sLfq6N53ZAfsfuym4130_assertion SIO_000772 25189770 NP1217047.RA-lUgxOZ6PsbZ_AAIpKf1f3Yi_2sLfq6N53ZAfsfuym4130_provenance.
- NP1217047.RA-lUgxOZ6PsbZ_AAIpKf1f3Yi_2sLfq6N53ZAfsfuym4130_assertion wasDerivedFrom befree-2016 NP1217047.RA-lUgxOZ6PsbZ_AAIpKf1f3Yi_2sLfq6N53ZAfsfuym4130_provenance.
- NP1217047.RA-lUgxOZ6PsbZ_AAIpKf1f3Yi_2sLfq6N53ZAfsfuym4130_assertion wasGeneratedBy ECO_0000203 NP1217047.RA-lUgxOZ6PsbZ_AAIpKf1f3Yi_2sLfq6N53ZAfsfuym4130_provenance.